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http://purl.uniprot.org/citations/15273740http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15273740http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15273740http://www.w3.org/2000/01/rdf-schema#comment"AMID, also called PRG3, is an AIF-homologous and mitochondria-associated protein that has been implicated in caspase-independent apoptosis. In this report, we demonstrated that human AMID gene promoter was activated by p53 in reporter gene assays. Chromatin immunoprecipitation experiments indicated that p53 could bind to human AMID promoter. Deletion mutagenesis indicated that human AMID promoter contains two p53-responsive elements. Furthermore, expression array analysis indicated that human AMID mRNA expression was downregulated in a majority of human tumors. Our findings point to the possibility that AMID is a p53-downstream gene involved in tumorigenesis."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.org/dc/terms/identifier"doi:10.1038/sj.onc.1207909"xsd:string
http://purl.uniprot.org/citations/15273740http://purl.org/dc/terms/identifier"doi:10.1038/sj.onc.1207909"xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/author"Wu M."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/author"Wu M."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/author"Tian Y."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/author"Tian Y."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/author"Su T."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/author"Su T."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/author"Zhai Z."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/author"Zhai Z."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/author"Xu L.-G."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/author"Xu L.-G."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/author"Shu H.-B."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/author"Shu H.-B."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/name"Oncogene"xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/name"Oncogene"xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/pages"6815-6819"xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/pages"6815-6819"xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/title"AMID is a p53-inducible gene downregulated in tumors."xsd:string
http://purl.uniprot.org/citations/15273740http://purl.uniprot.org/core/title"AMID is a p53-inducible gene downregulated in tumors."xsd:string