| http://purl.uniprot.org/citations/15280233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15280233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15280233 | http://www.w3.org/2000/01/rdf-schema#comment | "Null mutations in lin-35, the Caenorhabditis elegans ortholog of the mammalian Rb protein, cause no obvious morphological defects. Using a genetic approach to identify genes that may function redundantly with lin-35, we have isolated a mutation in the C. elegans psa-1 gene. lin-35; psa-1 double mutants display severe developmental defects leading to early larval arrest and adult sterility. The psa-1 gene has previously been shown to encode a C. elegans homolog of yeast SWI3, a critical component of the SWI/SNF complex, and has been shown to regulate asymmetric cell divisions during C. elegans development. We observed strong genetic interactions between psa-1 and lin-35 as well as a subset of the class B synMuv genes that include lin-37 and lin-9. Loss-of-function mutations in lin-35, lin-37, and lin-9 strongly enhanced the defects of asymmetric T cell division associated with a psa-1 mutation. Our results suggest that LIN-35/Rb and a certain class B synMuv proteins collaborate with the SWI/SNF protein complex to regulate the T cell division as well as other events essential for larval growth."xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.org/dc/terms/identifier | "doi:10.1534/genetics.103.024554"xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.org/dc/terms/identifier | "doi:10.1534/genetics.103.024554"xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/author | "Han M."xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/author | "Han M."xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/author | "Cui M."xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/author | "Cui M."xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/author | "Fay D.S."xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/author | "Fay D.S."xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/pages | "1177-1185"xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/pages | "1177-1185"xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/title | "lin-35/Rb cooperates with the SWI/SNF complex to control Caenorhabditis elegans larval development."xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/title | "lin-35/Rb cooperates with the SWI/SNF complex to control Caenorhabditis elegans larval development."xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/volume | "167"xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://purl.uniprot.org/core/volume | "167"xsd:string |
| http://purl.uniprot.org/citations/15280233 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15280233 |
| http://purl.uniprot.org/citations/15280233 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15280233 |
| http://purl.uniprot.org/citations/15280233 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15280233 |
| http://purl.uniprot.org/citations/15280233 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15280233 |