http://purl.uniprot.org/citations/15302849 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15302849 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15302849 | http://www.w3.org/2000/01/rdf-schema#comment | "Five Fc receptor homologs (FcRH1-5) possessing inhibitory and/or activating signaling motifs are differentially expressed during B cell differentiation in humans. In this analysis we describe their three mouse orthologs, moFcRH1, moFcRH2 and moFcRH3. The moFcRH genes are located in a chromosome 3 region that is syntenic with the FcRH locus on human chromosome 1. They encode proteins with 2-5 Ig-like domains that share 20-61% extracellular identity with their human counterparts. One moFcRH1 isoform lacks a transmembrane domain as do both moFcRH2 isoforms. The other moFcRH1 isoform and two moFcRH3 isoforms have transmembrane domains and cytoplasmic ITIM and ITAM-like consensus sequences implying their inhibitory or activating signaling potential. Whereas the moFcRH1 and moFcRH3 orthologs are preferentially expressed at different stages in B cell differentiation, the structurally novel moFcRH2 gene is expressed in non-lymphoid tissues. The highly restricted pattern of moFcRH3 expression suggests this member of the phylogenetically conserved FcRH family may have an important immunoregulatory role in marginal zone B cells."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.org/dc/terms/identifier | "doi:10.1093/intimm/dxh137"xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.org/dc/terms/identifier | "doi:10.1093/intimm/dxh137"xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/author | "Chen C.-C."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/author | "Chen C.-C."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/author | "Cooper M.D."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/author | "Cooper M.D."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/author | "Davis R.S."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/author | "Davis R.S."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/author | "Dennis G. Jr."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/author | "Dennis G. Jr."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/author | "Stephan R.P."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/author | "Stephan R.P."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/name | "Int. Immunol."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/name | "Int. Immunol."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/pages | "1343-1353"xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/pages | "1343-1353"xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/title | "Differential B cell expression of mouse Fc receptor homologs."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/title | "Differential B cell expression of mouse Fc receptor homologs."xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/volume | "16"xsd:string |
http://purl.uniprot.org/citations/15302849 | http://purl.uniprot.org/core/volume | "16"xsd:string |