http://purl.uniprot.org/citations/1530918 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1530918 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1530918 | http://www.w3.org/2000/01/rdf-schema#comment | "Tyrosine phosphorylation and dephosphorylating events have been shown to be central to the process of growth regulation and signal transduction. We report here, the identification of a new gene with a tyrosine phosphatase domain (EC 3.1.3.48) which is expressed exclusively in thymus and spleen. A cDNA of 2760 bp encodes a 339-amino acid, intracellular, single-domain tyrosine phosphatase. When expressed as a glutathionine-S-transferase fusion protein, efficient lysis of p-nitrophenyl phosphate is noted, indicating in vitro enzymatic activity of the cloned gene product. Normal mouse lymphocytes increase mRNA expression 10-15-fold upon stimulation with phytohemagglutinin, concanavalin A, lipopolysaccharide or anti-CD3 monoclonal antibody. This new hematopoietic tyrosine phosphatase, (HePTP), may play a role in the regulation of T and B lymphocyte development and signal transduction."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.org/dc/terms/identifier | "doi:10.1002/eji.1830220134"xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.org/dc/terms/identifier | "doi:10.1002/eji.1830220134"xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Suzuki H."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Suzuki H."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Mak T.W."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Mak T.W."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Zanke B."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Zanke B."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Pawson A."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Pawson A."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Kishihara K."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Kishihara K."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Mizzen L."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Mizzen L."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Minden M."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/author | "Minden M."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/name | "Eur. J. Immunol."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/name | "Eur. J. Immunol."xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/pages | "235-239"xsd:string |
http://purl.uniprot.org/citations/1530918 | http://purl.uniprot.org/core/pages | "235-239"xsd:string |