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http://purl.uniprot.org/citations/1535156http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1535156http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1535156http://www.w3.org/2000/01/rdf-schema#comment"During its unidirectional unwinding of DNA, RecBCD enzyme cuts one DNA strand near a properly oriented Chi site, a hotspot of homologous genetic recombination in Escherichia coli. We report here that individual DNA molecules containing two properly oriented Chi sites were cut with about 40% efficiency at one or the other Chi site but not detectably at both Chi sites. Furthermore, initial incubation of RecBCD with Chi-containing DNA reduced its ability both to unwind DNA and to cut at Chi sites on subsequently added DNA molecules much more than did initial incubation with Chi-free DNA; the nuclease activity was less severely affected. These results imply that RecBCD loses its Chi-cutting activity upon cutting at a single Chi site and provide a mechanism for ensuring single genetic exchanges near the ends of DNA molecules."xsd:string
http://purl.uniprot.org/citations/1535156http://purl.org/dc/terms/identifier"doi:10.1073/pnas.89.12.5226"xsd:string
http://purl.uniprot.org/citations/1535156http://purl.org/dc/terms/identifier"doi:10.1073/pnas.89.12.5226"xsd:string
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/author"Smith G.R."xsd:string
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/author"Smith G.R."xsd:string
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/author"Taylor A.F."xsd:string
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/author"Taylor A.F."xsd:string
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/pages"5226-5230"xsd:string
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/pages"5226-5230"xsd:string
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/title"RecBCD enzyme is altered upon cutting DNA at a chi recombination hotspot."xsd:string
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/title"RecBCD enzyme is altered upon cutting DNA at a chi recombination hotspot."xsd:string
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/volume"89"xsd:string
http://purl.uniprot.org/citations/1535156http://purl.uniprot.org/core/volume"89"xsd:string
http://purl.uniprot.org/citations/1535156http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1535156
http://purl.uniprot.org/citations/1535156http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1535156
http://purl.uniprot.org/citations/1535156http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1535156
http://purl.uniprot.org/citations/1535156http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1535156
http://purl.uniprot.org/uniprot/P04993http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/1535156
http://purl.uniprot.org/uniprot/P08394http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/1535156