| http://purl.uniprot.org/citations/15351640 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15351640 | http://www.w3.org/2000/01/rdf-schema#comment | "The heterogeneous nuclear ribonucleoprotein K protein is an RNA-binding protein found in several subcellular compartments where it is thought to be involved in signaling multiple processes that compose gene expression. K protein contains three K homology (KH) domains that mediate RNA-binding. We used a serial analysis of gene expression (SAGE)-based strategy, yeast three-hybrid screen, RNA pull-down assays and computational analysis to characterize K protein-associated RNAs. We demonstrate that K protein interacts with many sense and antisense nuclear and mitochondrial transcripts through both direct and indirect binding. The highly specific direct binding of transcripts to K protein is mediated by a consensus sequence comprising three C-rich patches. Structural analysis suggests a three-prong interaction model whereby each of the three KH domains binds one of the C-rich patches. Genome-wide and yeast three-hybrid clone analysis revealed that these sequences are located preferentially in the 3' untranslated regions, which are known to regulate mRNA translation and processing."xsd:string |
| http://purl.uniprot.org/citations/15351640 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jmb.2004.07.099"xsd:string |
| http://purl.uniprot.org/citations/15351640 | http://purl.uniprot.org/core/author | "Jain S."xsd:string |
| http://purl.uniprot.org/citations/15351640 | http://purl.uniprot.org/core/author | "Wyrwicz L.S."xsd:string |
| http://purl.uniprot.org/citations/15351640 | http://purl.uniprot.org/core/author | "Ostrowski J."xsd:string |
| http://purl.uniprot.org/citations/15351640 | http://purl.uniprot.org/core/author | "Bomsztyk K."xsd:string |
| http://purl.uniprot.org/citations/15351640 | http://purl.uniprot.org/core/author | "Klimek-Tomczak K."xsd:string |
| http://purl.uniprot.org/citations/15351640 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15351640 | http://purl.uniprot.org/core/name | "J Mol Biol"xsd:string |
| http://purl.uniprot.org/citations/15351640 | http://purl.uniprot.org/core/pages | "1131-1141"xsd:string |
| http://purl.uniprot.org/citations/15351640 | http://purl.uniprot.org/core/title | "Characterization of hnRNP K protein-RNA interactions."xsd:string |
| http://purl.uniprot.org/citations/15351640 | http://purl.uniprot.org/core/volume | "342"xsd:string |
| http://purl.uniprot.org/citations/15351640 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15351640 |
| http://purl.uniprot.org/citations/15351640 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15351640 |
| http://purl.uniprot.org/uniprot/P38151#attribution-497CA7325B20020E2DAE73D8CAD8ACCE | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15351640 |
| http://purl.uniprot.org/uniprot/#_P38151-mappedCitation-15351640 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15351640 |
| http://purl.uniprot.org/uniprot/#_P38199-mappedCitation-15351640 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15351640 |
| http://purl.uniprot.org/uniprot/P38199 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15351640 |
| http://purl.uniprot.org/uniprot/P38151 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15351640 |