| http://purl.uniprot.org/citations/15353235 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15353235 | http://www.w3.org/2000/01/rdf-schema#comment | "Niemann-Pick disease type C (NP-C) is a progressive neurological disorder of lipid metabolism. The Balb/C npc1 mutant strain is a genetically authentic murine model of NPC, which reproduce the clinical and histologic features of human NP-C. In the present study, we show that cholecystokinin (CCK)-immunoreactive fibers in the thalamic VPL nuclei, which are densely distributed in controls, degenerate in NPC mice. This degeneration is associated with the appearance of CCK-immunoreactive axonal spheroids containing characteristic intracellular inclusions of NP-C. These observations provide supportive evidence of the occurrence of dying-back axonopathy of neurons in the dorsal column nuclei in this mouse model."xsd:string |
| http://purl.uniprot.org/citations/15353235 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.brainres.2004.06.037"xsd:string |
| http://purl.uniprot.org/citations/15353235 | http://purl.uniprot.org/core/author | "Ohno K."xsd:string |
| http://purl.uniprot.org/citations/15353235 | http://purl.uniprot.org/core/author | "Ninomiya H."xsd:string |
| http://purl.uniprot.org/citations/15353235 | http://purl.uniprot.org/core/author | "Ukita Y."xsd:string |
| http://purl.uniprot.org/citations/15353235 | http://purl.uniprot.org/core/author | "Ohara S."xsd:string |
| http://purl.uniprot.org/citations/15353235 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15353235 | http://purl.uniprot.org/core/name | "Brain Res"xsd:string |
| http://purl.uniprot.org/citations/15353235 | http://purl.uniprot.org/core/pages | "244-246"xsd:string |
| http://purl.uniprot.org/citations/15353235 | http://purl.uniprot.org/core/title | "Degeneration of cholecystokinin-immunoreactive afferents to the VPL thalamus in a mouse model of Niemann-Pick disease type C."xsd:string |
| http://purl.uniprot.org/citations/15353235 | http://purl.uniprot.org/core/volume | "1022"xsd:string |
| http://purl.uniprot.org/citations/15353235 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15353235 |
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