http://purl.uniprot.org/citations/15364412 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15364412 | http://www.w3.org/2000/01/rdf-schema#comment | "Deposition of amyloid beta (A beta) into extracellular plaques is a pathologic characteristic of Alzheimer's disease. Plasmin, neprilysin, endothelin-converting enzyme and insulin-degrading enzyme (IDE) have each been implicated in A beta degradation; data supporting the role of the latter three enzymes have included increased levels of endogenous murine A beta in mice genetically deficient for the respective enzyme. In this study, we sought to determine if plasminogen deficiency increases endogenous A beta. We report that plasminogen deficiency did not result in an A beta increase in the brain or in the plasma of adult mice. Hence, although plasmin is potentially important in the degradation of A beta aggregates, we interpret these data as suggesting that plasmin does not regulate steady-state A beta levels in non-pathologic conditions."xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.neulet.2004.07.011"xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/author | "Younkin S.G."xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/author | "Degen J.L."xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/author | "Simpson J."xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/author | "Estus S."xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/author | "Tucker H.M."xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/author | "McGillis J.P."xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/author | "Younkin L.H."xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/author | "Kihiko-Ehmann M."xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/name | "Neurosci Lett"xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/pages | "285-289"xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/title | "Plasmin deficiency does not alter endogenous murine amyloid beta levels in mice."xsd:string |
http://purl.uniprot.org/citations/15364412 | http://purl.uniprot.org/core/volume | "368"xsd:string |
http://purl.uniprot.org/citations/15364412 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15364412 |
http://purl.uniprot.org/citations/15364412 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15364412 |
http://purl.uniprot.org/uniprot/#_E9PV24-mappedCitation-15364412 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15364412 |
http://purl.uniprot.org/uniprot/#_Q3V1T9-mappedCitation-15364412 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15364412 |
http://purl.uniprot.org/uniprot/#_P20918-mappedCitation-15364412 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15364412 |
http://purl.uniprot.org/uniprot/#_Q6TCI0-mappedCitation-15364412 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15364412 |
http://purl.uniprot.org/uniprot/Q3V1T9 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15364412 |
http://purl.uniprot.org/uniprot/Q6TCI0 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15364412 |
http://purl.uniprot.org/uniprot/P20918 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15364412 |