http://purl.uniprot.org/citations/15380299 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15380299 | http://www.w3.org/2000/01/rdf-schema#comment | "The present study was aimed at investigating whether two-kidney, one clip (2K1C) hypertension is associated with an enhanced central adrenergic activity. Rats were made 2K1C hypertensive, and the expression of Fos-like immunoreactivity (FLI) and phenylethanalamine N-methyltransferase (PNMT)-immunoreactivity was determined in the brain areas related to the cardiovascular regulation. In 2K1C hypertension, the basal Fos-immunoreactivity was significantly increased in rostral ventrolateral medulla (RVLM), paraventricular nucleus (PVN), and supraoptic nucleus (SON). PNMT-immunoreactivities were noted in RVLM, but not in PVN or SON. Intracerebroventricular administration of angiotensin II (AII) markedly increased Fos-immunoreactivities, the degree of which was greater in hypertension. Furthermore, AII increased the ratio of PNMT-positive/Fos-positive neurons in RVLM in hypertension. It is suggested that the responsiveness to AII of the central adrenergic system is enhanced in 2K1C hypertension."xsd:string |
http://purl.uniprot.org/citations/15380299 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.neulet.2004.07.029"xsd:string |
http://purl.uniprot.org/citations/15380299 | http://purl.uniprot.org/core/author | "Kim W.J."xsd:string |
http://purl.uniprot.org/citations/15380299 | http://purl.uniprot.org/core/author | "Jung J.Y."xsd:string |
http://purl.uniprot.org/citations/15380299 | http://purl.uniprot.org/core/author | "Lee J.U."xsd:string |
http://purl.uniprot.org/citations/15380299 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15380299 | http://purl.uniprot.org/core/name | "Neurosci Lett"xsd:string |
http://purl.uniprot.org/citations/15380299 | http://purl.uniprot.org/core/pages | "14-18"xsd:string |
http://purl.uniprot.org/citations/15380299 | http://purl.uniprot.org/core/title | "Enhanced activity of central adrenergic neurons in two-kidney, one clip hypertension in Sprague-Dawley rats."xsd:string |
http://purl.uniprot.org/citations/15380299 | http://purl.uniprot.org/core/volume | "369"xsd:string |
http://purl.uniprot.org/citations/15380299 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15380299 |
http://purl.uniprot.org/citations/15380299 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15380299 |
http://purl.uniprot.org/uniprot/P10937#attribution-87DBFCF6340BCA2FDEE748BB2F245915 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15380299 |
http://purl.uniprot.org/uniprot/#_P10937-mappedCitation-15380299 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15380299 |
http://purl.uniprot.org/uniprot/#_M0RCR5-mappedCitation-15380299 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15380299 |
http://purl.uniprot.org/uniprot/M0RCR5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15380299 |
http://purl.uniprot.org/uniprot/P10937 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15380299 |