| http://purl.uniprot.org/citations/15388334 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15388334 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15388334 | http://www.w3.org/2000/01/rdf-schema#comment | "ALS2, the causative gene product for juvenile recessive amyotrophic lateral sclerosis (ALS2), is a guanine-nucleotide exchange factor for the small GTPase Rab5. Here, we report a novel ALS2 homologous gene, ALS2 C-terminal like (ALS2CL), which encodes a 108-kD ALS2CL protein. ALS2CL exhibited a specific but a relatively weak Rab5-GEF activity with accompanying rather strong Rab5-binding properties. In HeLa cells, co-expression of ALS2CL and Rab5A resulted in a unique tubulation phenotype of endosome compartments with significant colocalization of ALS2CL and Rab5A. These results suggest that ALS2CL is a novel factor modulating the Rab5-mediated endosome dynamics in the cells."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2004.07.092"xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2004.07.092"xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Hadano S."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Hadano S."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Ikeda J.-E."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Ikeda J.-E."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Yanagisawa Y."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Yanagisawa Y."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Kunita R."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Kunita R."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Mizumura H."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Mizumura H."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Otomo A."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Otomo A."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Showguchi-Miyata J."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Showguchi-Miyata J."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Suzuki-Utsunomiya K."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/author | "Suzuki-Utsunomiya K."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/15388334 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |