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| http://purl.uniprot.org/citations/15449178 | http://www.w3.org/2000/01/rdf-schema#comment | "Induction of gelatinase in eosinophilic meningitis of BALB/c-strain mice was caused by Angiostrongylus cantonensis. Time-course studies showed that the molecular weight of 94-kDa gelatinase was detected at day 10 post-inoculation (PI), and reached a high intensity from days 15 to 25 PI. The 94-kDa gelatinase activity was clearly inhibited by EDTA and 1,10-phenanthroline, but not by leupeptin and phenylmethanesulphonyl fluoride. When immunoblots were performed using specific antiserums against the 94-kDa gelatinase B (matrix metalloproteinase-9; MMP-9) with cerebrospinal fluid (CSF), the 94-kDa immunopositive band was MMP-9. Immunohistochemistry studies demonstrated MMP-9 localisation within eosinophils and macrophages. The increased MMP-9 activity was closely associated with the rapid rise of CSF eosinophils, and the inflammatory reaction of the subarachnoid space. In contrast to changes in MMP-9, MMP-2 activity was constitutive and unaffected in this parasitic meningitis. These results show that MMP-9 was associated with eosinophilic meningitis, and that the enzyme may be a useful marker for angiostrongyliasis meningitis."xsd:string |
| http://purl.uniprot.org/citations/15449178 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00436-004-1196-3"xsd:string |
| http://purl.uniprot.org/citations/15449178 | http://purl.uniprot.org/core/author | "Lee H.H."xsd:string |
| http://purl.uniprot.org/citations/15449178 | http://purl.uniprot.org/core/author | "Chen K.M."xsd:string |
| http://purl.uniprot.org/citations/15449178 | http://purl.uniprot.org/core/author | "Chou H.L."xsd:string |
| http://purl.uniprot.org/citations/15449178 | http://purl.uniprot.org/core/author | "Lai S.C."xsd:string |
| http://purl.uniprot.org/citations/15449178 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15449178 | http://purl.uniprot.org/core/name | "Parasitol Res"xsd:string |
| http://purl.uniprot.org/citations/15449178 | http://purl.uniprot.org/core/pages | "321-328"xsd:string |
| http://purl.uniprot.org/citations/15449178 | http://purl.uniprot.org/core/title | "Association of matrix metalloproteinase-9 in eosinophilic meningitis of BALB/c mice caused by Angiostrongylus cantonensis."xsd:string |
| http://purl.uniprot.org/citations/15449178 | http://purl.uniprot.org/core/volume | "94"xsd:string |
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