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http://purl.uniprot.org/citations/15474462http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15474462http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15474462http://www.w3.org/2000/01/rdf-schema#comment"Cdc7 expression repressor (CR)/periphilin has been originally cloned as an interactor with periplakin, a precursor of the cornified cell envelope, and suggested to constitute a new type of nuclear matrix. We here show that CR/periphilin is a ubiquitously expressed nuclear protein with speckled distribution. Overexpression of CR/periphilin induces S-phase arrest. Analysis of expression of regulators involved in DNA replication has revealed that both mRNA and protein expression of Cdc7, a regulator of the initiation and continuation of DNA replication, are markedly downregulated by overexpression of CR/periphilin. However, co-expression of Cdc7 only marginally rescues S-phase arrest induced by CR, indicating that CR retards S-phase progression by modifying expression of some genes including Cdc7, which are involved in progression of DNA replication or coordination of DNA replication and S-phase progression."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2004.09.083"xsd:string
http://purl.uniprot.org/citations/15474462http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2004.09.083"xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Suzuki H."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Suzuki H."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Matsuoka M."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Matsuoka M."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Kurita M."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Kurita M."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Mizumoto K."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Mizumoto K."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Nishimoto I."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Nishimoto I."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Ogata E."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Ogata E."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Aiso S."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Aiso S."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Masai H."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/author"Masai H."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/15474462http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string