| http://purl.uniprot.org/citations/15475296 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15475296 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15475296 | http://www.w3.org/2000/01/rdf-schema#comment | "Apolipophorin-III (apoLp-III) is a hemolymph protein whose function is to facilitate lipid transport in an aqueous medium. Recently, apoLp-III in Galleria mellonella larvae was shown to play an unexpected role in insect immune activation. We identified the cDNA sequence of Hyphantria cunea apoLp-III by oligonucleotide-primed amplification, and 5'- and 3'-RACE PCR. Since H. cunea has an unusually low level of apoLp-III in the hemolymph, a recombinant apoLp-III was overexpressed using a baculovirus expression system to investigate its biological activity. Recombinant apoLp-III and/or Escherichia coli were injected into the hemocoel of last instar larvae, and the expression of antimicrobial peptide from fat body was determined by Northern blot. Injection of apoLp-III as well as E. coli induced slight up-regulation of its transcription rate in fat body, whereas the expression of antimicrobial peptide was dramatically induced by the injection of apoLp-III and E. coli. H. cunea hemocytes had apoLp-III in the granules and expressed its transcript, albeit at a much lower level than in the fat body. Upon bacterial injection, a subpopulation of hemocytes showed degranulation and degradation. Local discharge of apoLp-III from hemocytes caused by the injection of E. coli might be related to the immune response through an unknown mechanism."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ibmb.2004.05.005"xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ibmb.2004.05.005"xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Park S.-Y."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Park S.-Y."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Kim H.-J."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Kim H.-J."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Han Y.-S."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Han Y.-S."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Je H.-J."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Je H.-J."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Jin B.-R."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Jin B.-R."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Kang Y.-J."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Kang Y.-J."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Lee I.-H."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Lee I.-H."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Seo S.-J."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Seo S.-J."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Yun C.-Y."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Yun C.-Y."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Yun H.-K."xsd:string |
| http://purl.uniprot.org/citations/15475296 | http://purl.uniprot.org/core/author | "Yun H.-K."xsd:string |