http://purl.uniprot.org/citations/15477346 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15477346 | http://www.w3.org/2000/01/rdf-schema#comment | "It is well established that T lymphocytes undergo homeostatic proliferation in lymphopenic environment. The homeostatic proliferation requires recognition of the major histocompatibility complex on the host. Recent studies have demonstrated that costimulation-mediated CD28, 4-1BB, and CD40 is not required for T cell homeostatic proliferation. It has been suggested that homeostatic proliferation is costimulation independent. Here, we report that T cells from mice with a targeted mutation of CD24 have a remarkably reduced rate of proliferation when adoptively transferred into syngeneic lymphopenic hosts. The reduced proliferation cannot be attributed to abnormal survival and homing properties of the CD24-deficient T cells. T cell proliferation in allogeneic hosts is less affected by this mutation. These results demonstrate a novel function of CD24 expressed on T cells. Thus, although distinct costimulatory molecules are involved in antigen-driven proliferation and homeostatic proliferation, both processes can be modulated by costimulatory molecules."xsd:string |
http://purl.uniprot.org/citations/15477346 | http://purl.org/dc/terms/identifier | "doi:10.1084/jem.20040779"xsd:string |
http://purl.uniprot.org/citations/15477346 | http://purl.uniprot.org/core/author | "Liu Y."xsd:string |
http://purl.uniprot.org/citations/15477346 | http://purl.uniprot.org/core/author | "Zheng P."xsd:string |
http://purl.uniprot.org/citations/15477346 | http://purl.uniprot.org/core/author | "Li O."xsd:string |
http://purl.uniprot.org/citations/15477346 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15477346 | http://purl.uniprot.org/core/name | "J Exp Med"xsd:string |
http://purl.uniprot.org/citations/15477346 | http://purl.uniprot.org/core/pages | "1083-1089"xsd:string |
http://purl.uniprot.org/citations/15477346 | http://purl.uniprot.org/core/title | "CD24 expression on T cells is required for optimal T cell proliferation in lymphopenic host."xsd:string |
http://purl.uniprot.org/citations/15477346 | http://purl.uniprot.org/core/volume | "200"xsd:string |
http://purl.uniprot.org/citations/15477346 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15477346 |
http://purl.uniprot.org/citations/15477346 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15477346 |
http://purl.uniprot.org/uniprot/P24807#attribution-1CDA94AE73C34764FBDF3D9D81C74620 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15477346 |
http://purl.uniprot.org/uniprot/P24807#attribution-257BAB3445F7653C94C57E5734A05644 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15477346 |
http://purl.uniprot.org/uniprot/P15379#attribution-257BAB3445F7653C94C57E5734A05644 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15477346 |
http://purl.uniprot.org/uniprot/P18337#attribution-257BAB3445F7653C94C57E5734A05644 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15477346 |
http://purl.uniprot.org/uniprot/#_A0A0A6YW25-mappedCitation-15477346 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15477346 |
http://purl.uniprot.org/uniprot/#_A0A1L1ST40-mappedCitation-15477346 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15477346 |
http://purl.uniprot.org/uniprot/#_A0A1L1SUX8-mappedCitation-15477346 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15477346 |
http://purl.uniprot.org/uniprot/#_P15379-mappedCitation-15477346 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15477346 |
http://purl.uniprot.org/uniprot/#_A0A1L1SQ70-mappedCitation-15477346 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15477346 |
http://purl.uniprot.org/uniprot/#_A0A1L1SRS7-mappedCitation-15477346 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15477346 |
http://purl.uniprot.org/uniprot/#_A2APM1-mappedCitation-15477346 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15477346 |
http://purl.uniprot.org/uniprot/#_A2APM2-mappedCitation-15477346 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15477346 |