http://purl.uniprot.org/citations/15485813 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15485813 | http://www.w3.org/2000/01/rdf-schema#comment | "The uncoupling protein 2, UCP2, is a member of a family of inner mitochondrial membrane ion carriers involved in a host of metabolic processes. UCP2 protein is encoded by nuclear genome, but the protein is found exclusively in the mitochondria. The heterogeneous nuclear ribonucleoprotein K (hnRNPK) is an RNA-binding protein involved in many processes that compose gene expression, including mRNA processing and translation. The yeast three-hybrid screen revealed K protein bound to ucp2 mRNA through sites located in the 3'-untranslated region of the transcript. ucp2 mRNA-K protein complexes were associated with polysome-coated mitochondria. Expression of exogenous K protein augmented the insulin-induced mitochondrial level of UCP2 protein that was not accompanied by a corresponding increase in ucp2 mRNA. These results suggest the insulin stimulates translation of ucp2 mRNA in a process that involves K protein."xsd:string |
http://purl.uniprot.org/citations/15485813 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m406753200"xsd:string |
http://purl.uniprot.org/citations/15485813 | http://purl.uniprot.org/core/author | "Wyrwicz L.S."xsd:string |
http://purl.uniprot.org/citations/15485813 | http://purl.uniprot.org/core/author | "Ostrowski J."xsd:string |
http://purl.uniprot.org/citations/15485813 | http://purl.uniprot.org/core/author | "Bomsztyk K."xsd:string |
http://purl.uniprot.org/citations/15485813 | http://purl.uniprot.org/core/author | "Mikula M."xsd:string |
http://purl.uniprot.org/citations/15485813 | http://purl.uniprot.org/core/author | "Klimek-Tomczak K."xsd:string |
http://purl.uniprot.org/citations/15485813 | http://purl.uniprot.org/core/author | "Schullery D.S."xsd:string |
http://purl.uniprot.org/citations/15485813 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15485813 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
http://purl.uniprot.org/citations/15485813 | http://purl.uniprot.org/core/pages | "54599-54609"xsd:string |
http://purl.uniprot.org/citations/15485813 | http://purl.uniprot.org/core/title | "Heterogeneous nuclear ribonucleoprotein K enhances insulin-induced expression of mitochondrial UCP2 protein."xsd:string |
http://purl.uniprot.org/citations/15485813 | http://purl.uniprot.org/core/volume | "279"xsd:string |
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