http://purl.uniprot.org/citations/15494480 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15494480 | http://www.w3.org/2000/01/rdf-schema#comment | "CD160 is an Ig-like activating NK cell receptor expressed on the majority of circulating NK cells. This population corresponds to the nonproliferating, highly cytolytic, CD56dimCD16+ subset. CD160 engagement by HLA-C molecules mediates cytotoxic function. In this study, we report that upon specific activation by the physiological ligand HLA-C, or Ab cross-linking, CD160+ peripheral blood NK cells produce IFN-gamma, TNF-alpha, and IL-6. This unique CD160-mediated cytokine production differs from the one observed after CD16 engagement whose expression is also restricted to the CD56dim cytotoxic NK cell subset. As already reported for the CD160-mediated cytotoxic effector function, CD160-mediated cytokine production by peripheral blood-NK cells is negatively controlled by the killer Ig-like receptor CD158b. Thus, the CD160 receptor represents a unique triggering surface molecule expressed by cytotoxic NK cells that participates in the inflammatory response and determines the type of subsequent specific immunity."xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.173.9.5349"xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/author | "Aguerre-Girr M."xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/author | "Barakonyi A."xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/author | "Bensussan A."xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/author | "Le Bouteiller P."xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/author | "Marie-Cardine A."xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/author | "Polgar B."xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/author | "Rabot M."xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/author | "Schiavon V."xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/pages | "5349-5354"xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/title | "Cutting edge: engagement of CD160 by its HLA-C physiological ligand triggers a unique cytokine profile secretion in the cytotoxic peripheral blood NK cell subset."xsd:string |
http://purl.uniprot.org/citations/15494480 | http://purl.uniprot.org/core/volume | "173"xsd:string |
http://purl.uniprot.org/citations/15494480 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15494480 |
http://purl.uniprot.org/citations/15494480 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15494480 |
http://purl.uniprot.org/uniprot/O95971#attribution-C07028DBF404E8E6888BFBD475041C83 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15494480 |
http://purl.uniprot.org/uniprot/#_O95971-mappedCitation-15494480 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15494480 |
http://purl.uniprot.org/uniprot/#_Q6FH89-mappedCitation-15494480 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15494480 |
http://purl.uniprot.org/uniprot/O95971 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15494480 |
http://purl.uniprot.org/uniprot/Q6FH89 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15494480 |