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http://purl.uniprot.org/citations/15494480http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15494480http://www.w3.org/2000/01/rdf-schema#comment"CD160 is an Ig-like activating NK cell receptor expressed on the majority of circulating NK cells. This population corresponds to the nonproliferating, highly cytolytic, CD56dimCD16+ subset. CD160 engagement by HLA-C molecules mediates cytotoxic function. In this study, we report that upon specific activation by the physiological ligand HLA-C, or Ab cross-linking, CD160+ peripheral blood NK cells produce IFN-gamma, TNF-alpha, and IL-6. This unique CD160-mediated cytokine production differs from the one observed after CD16 engagement whose expression is also restricted to the CD56dim cytotoxic NK cell subset. As already reported for the CD160-mediated cytotoxic effector function, CD160-mediated cytokine production by peripheral blood-NK cells is negatively controlled by the killer Ig-like receptor CD158b. Thus, the CD160 receptor represents a unique triggering surface molecule expressed by cytotoxic NK cells that participates in the inflammatory response and determines the type of subsequent specific immunity."xsd:string
http://purl.uniprot.org/citations/15494480http://purl.org/dc/terms/identifier"doi:10.4049/jimmunol.173.9.5349"xsd:string
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/author"Aguerre-Girr M."xsd:string
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/author"Barakonyi A."xsd:string
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/author"Bensussan A."xsd:string
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/author"Le Bouteiller P."xsd:string
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/author"Marie-Cardine A."xsd:string
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/author"Polgar B."xsd:string
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/author"Rabot M."xsd:string
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/author"Schiavon V."xsd:string
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/name"J Immunol"xsd:string
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/pages"5349-5354"xsd:string
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/title"Cutting edge: engagement of CD160 by its HLA-C physiological ligand triggers a unique cytokine profile secretion in the cytotoxic peripheral blood NK cell subset."xsd:string
http://purl.uniprot.org/citations/15494480http://purl.uniprot.org/core/volume"173"xsd:string
http://purl.uniprot.org/citations/15494480http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15494480
http://purl.uniprot.org/citations/15494480http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15494480
http://purl.uniprot.org/uniprot/O95971#attribution-C07028DBF404E8E6888BFBD475041C83http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/15494480
http://purl.uniprot.org/uniprot/#_O95971-mappedCitation-15494480http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15494480
http://purl.uniprot.org/uniprot/#_Q6FH89-mappedCitation-15494480http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15494480
http://purl.uniprot.org/uniprot/O95971http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/15494480
http://purl.uniprot.org/uniprot/Q6FH89http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/15494480