| http://purl.uniprot.org/citations/15497139 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15497139 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15497139 | http://www.w3.org/2000/01/rdf-schema#comment | "Apoptosis is fundamental to normal vertebrate development. A dramatic example of postembryonic development involving apoptosis is tail regression during amphibian metamorphosis. Earlier studies led us to propose a functional role for the pro-apoptotic protein Bax in tadpole tail regression. However, its physiological relevance has never been analyzed. We have now cloned a cDNA encoding Xenopus laevis bax (xlbax) and used in vivo gene transfer in tail muscle to analyze the effects of xlbax overexpression. Furthermore, by using an antisense strategy in a similar experimental paradigm, xlbax antisense mRNA was shown to block the apoptotic effects of xlbax and protect against apoptosis in metamorphosing tadpoles. Our results suggest that xlbax is a regulator of muscle fiber death in the regressing tail during metamorphosis."xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.org/dc/terms/identifier | "doi:10.1002/dvdy.20166"xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/author | "Demeneix B.A."xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/author | "Demeneix B.A."xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/author | "Sachs L.M."xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/author | "Sachs L.M."xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/author | "Le Mevel S."xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/author | "Le Mevel S."xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/name | "Dev. Dyn."xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/name | "Dev Dyn"xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/pages | "671-682"xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/pages | "671-682"xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/title | "Implication of bax in Xenopus laevis tail regression at metamorphosis."xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/title | "Implication of bax in Xenopus laevis tail regression at metamorphosis."xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/volume | "231"xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://purl.uniprot.org/core/volume | "231"xsd:string |
| http://purl.uniprot.org/citations/15497139 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15497139 |
| http://purl.uniprot.org/citations/15497139 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15497139 |
| http://purl.uniprot.org/citations/15497139 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15497139 |
| http://purl.uniprot.org/citations/15497139 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15497139 |
| http://purl.uniprot.org/uniprot/Q98U13 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/15497139 |