| http://purl.uniprot.org/citations/15509555 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15509555 | http://www.w3.org/2000/01/rdf-schema#comment | "p53 is known to repress transcription of a number of genes, but the mechanism of p53 recruitment to these target genes is unknown. The c-myb proto-oncogene product (c-Myb) positively regulates proliferation of immature hematopoietic cells, whereas p53 blocks cell cycle progression. Here, we demonstrate that p53 inhibits c-Myb-induced transcription and transformation by directly binding to c-Myb. The ability of c-Myb to maintain the undifferentiated state of M1 cells was also suppressed by p53. p53 did not affect the ability of c-Myb to bind to DNA but formed a ternary complex with the corepressor mSin3A and c-Myb. Thus, p53 antagonizes c-Myb by recruiting mSin3A to down-regulate specific Myb target genes."xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m411658200"xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/author | "Ishii S."xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/author | "Jin W."xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/author | "Shirakawa M."xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/author | "Nomura T."xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/author | "Gonda T.J."xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/author | "Tanikawa J."xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/author | "Kokura K."xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/author | "Baba D."xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/author | "Macmillan E.M."xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/author | "Shinagawa T."xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/pages | "55393-55400"xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/title | "p53 suppresses c-Myb-induced trans-activation and transformation by recruiting the corepressor mSin3A."xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://purl.uniprot.org/core/volume | "279"xsd:string |
| http://purl.uniprot.org/citations/15509555 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15509555 |
| http://purl.uniprot.org/citations/15509555 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15509555 |
| http://purl.uniprot.org/uniprot/#_A0A087WPA7-mappedCitation-15509555 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15509555 |
| http://purl.uniprot.org/uniprot/#_A0A0C4DG19-mappedCitation-15509555 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15509555 |
| http://purl.uniprot.org/uniprot/#_B3KQE3-mappedCitation-15509555 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15509555 |
| http://purl.uniprot.org/uniprot/#_E9Q2L1-mappedCitation-15509555 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15509555 |
| http://purl.uniprot.org/uniprot/#_E9PXF9-mappedCitation-15509555 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15509555 |