| http://purl.uniprot.org/citations/15509774 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15509774 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15509774 | http://www.w3.org/2000/01/rdf-schema#comment | "The Alagille Syndrome (AGS) is a heritable disorder affecting the liver and other organs. Causative dominant mutations in human Jagged 1 have been identified in most AGS patients. Related organ defects occur in mice that carry jagged 1 and notch 2 mutations. Multiple jagged and notch genes are expressed in the developing zebrafish liver. Compound jagged and notch gene knockdowns alter zebrafish biliary, kidney, pancreatic, cardiac and craniofacial development in a manner compatible with an AGS phenocopy. These data confirm an evolutionarily conserved role for Notch signaling in vertebrate liver development, and support the zebrafish as a model system for diseases of the human biliary system."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.01411"xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Oda T."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Oda T."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Pack M."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Pack M."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Chandrasekharappa S."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Chandrasekharappa S."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Matthews R.P."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Matthews R.P."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Chitnis A."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Chitnis A."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Lorent K."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Lorent K."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Yeo S.Y."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/author | "Yeo S.Y."xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/name | "Development"xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/name | "Development"xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/pages | "5753-5766"xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/pages | "5753-5766"xsd:string |
| http://purl.uniprot.org/citations/15509774 | http://purl.uniprot.org/core/title | "Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopy."xsd:string |