| http://purl.uniprot.org/citations/15531893 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15531893 | http://www.w3.org/2000/01/rdf-schema#comment | "The heterodimeric Ku complex affects telomere structure in diverse organisms. We report here that in the absence of Ku, the catalytic subunit of telomerase, Est2p, was not telomere-associated in G1 phase, and its association in late S phase was decreased. The telomere association of Est1p, a telomerase component that binds telomeres only in late S phase, was also reduced in the absence of Ku. The effects of Ku on telomerase binding require a 48-nucleotide (nt) stem-loop region of TLC1 telomerase RNA. Ku interacts with TLC1 RNA via this 48-nt region throughout the cell cycle, but this interaction was reduced after telomere replication. These data support a model in which Ku recruits telomerase to telomeres in G1 phase when telomerase is inactive and promotes telomerase-mediated telomere lengthening in late S phase."xsd:string |
| http://purl.uniprot.org/citations/15531893 | http://purl.org/dc/terms/identifier | "doi:10.1038/nsmb854"xsd:string |
| http://purl.uniprot.org/citations/15531893 | http://purl.uniprot.org/core/author | "Zakian V.A."xsd:string |
| http://purl.uniprot.org/citations/15531893 | http://purl.uniprot.org/core/author | "Fisher T.S."xsd:string |
| http://purl.uniprot.org/citations/15531893 | http://purl.uniprot.org/core/author | "Taggart A.K."xsd:string |
| http://purl.uniprot.org/citations/15531893 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15531893 | http://purl.uniprot.org/core/name | "Nat Struct Mol Biol"xsd:string |
| http://purl.uniprot.org/citations/15531893 | http://purl.uniprot.org/core/pages | "1198-1205"xsd:string |
| http://purl.uniprot.org/citations/15531893 | http://purl.uniprot.org/core/title | "Cell cycle-dependent regulation of yeast telomerase by Ku."xsd:string |
| http://purl.uniprot.org/citations/15531893 | http://purl.uniprot.org/core/volume | "11"xsd:string |
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