http://purl.uniprot.org/citations/15541366 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15541366 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15541366 | http://www.w3.org/2000/01/rdf-schema#comment | "p73 is a transcriptional activator related to tumor suppressor p53 and regulates differentiation, cell-cycle arrest, and apoptosis. Recently, zebrafish p73 (zp73alpha) was isolated and shown to be required for zebrafish embryogenesis. In this study, we isolated a novel splicing-variant of zp73 mRNA, which was generated by the use of an alternative splicing acceptor site, and designated it as zp73theta;. The zp73theta; mRNA encoded a carboxy-terminal structure distinct from that of zp73alpha. Whereas the expression level of zp73theta; mRNA was much lower than that of zp73alpha in zebrafish adult tissues, it was relatively high and fluctuated during embryogenesis. Using Saos-2 cells for a transient reporter assay, we found that zp73theta;, but not zp73alpha, had strong transcriptional activity when the experiments were performed at 34 degrees C. In addition, zp73theta; had the ability to suppress the growth of Saos-2 cells and to cause the developmental defects in zebrafish. These data indicated that zp73theta; could work as a transcriptional activator in zebrafish."xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2004.10.109"xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2004.10.109"xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/author | "Arai K."xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/author | "Arai K."xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/author | "Watanabe S."xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/author | "Watanabe S."xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/author | "Satoh S."xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/author | "Satoh S."xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/pages | "835-842"xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/pages | "835-842"xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/title | "Identification of a novel splicing form of zebrafish p73 having a strong transcriptional activity."xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/title | "Identification of a novel splicing form of zebrafish p73 having a strong transcriptional activity."xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/volume | "325"xsd:string |
http://purl.uniprot.org/citations/15541366 | http://purl.uniprot.org/core/volume | "325"xsd:string |
http://purl.uniprot.org/citations/15541366 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15541366 |
http://purl.uniprot.org/citations/15541366 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15541366 |
http://purl.uniprot.org/citations/15541366 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15541366 |
http://purl.uniprot.org/citations/15541366 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15541366 |