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http://purl.uniprot.org/citations/15543138http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15543138http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15543138http://www.w3.org/2000/01/rdf-schema#comment"Gastrulation movements are critical for establishing the three principal germ layers and the basic architecture of vertebrate embryos. Although the individual molecules and pathways involved are not clearly understood, non-canonical Wnt signals are known to participate in developmental processes, including planar cell polarity and directed cell rearrangements. Here we demonstrate that the dual-specificity transcriptional repressor Kaiso, first identified in association with p120-catenin, is required for Xenopus gastrulation movements. In addition, depletion of xKaiso results in increased expression of the non-canonical xWnt11, which contributes to the xKaiso knockdown phenotype as it is significantly rescued by dominant-negative Wnt11. We further demonstrate that xWnt11 is a direct gene target of xKaiso and that p120-catenin association relieves xKaiso repression in vivo. Our results indicate that p120-catenin and Kaiso are essential components of a new developmental gene regulatory pathway that controls vertebrate morphogenesis."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.org/dc/terms/identifier"doi:10.1038/ncb1191"xsd:string
http://purl.uniprot.org/citations/15543138http://purl.org/dc/terms/identifier"doi:10.1038/ncb1191"xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Ji H."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Ji H."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Daniel J.M."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Daniel J.M."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Kim S.-W."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Kim S.-W."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Sater A.K."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Sater A.K."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"McCrea P.D."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"McCrea P.D."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Park J.-I."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Park J.-I."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Otchere A.A."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Otchere A.A."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Spring C.M."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/author"Spring C.M."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/name"Nat. Cell Biol."xsd:string
http://purl.uniprot.org/citations/15543138http://purl.uniprot.org/core/name"Nat. Cell Biol."xsd:string