http://purl.uniprot.org/citations/15543138 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15543138 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15543138 | http://www.w3.org/2000/01/rdf-schema#comment | "Gastrulation movements are critical for establishing the three principal germ layers and the basic architecture of vertebrate embryos. Although the individual molecules and pathways involved are not clearly understood, non-canonical Wnt signals are known to participate in developmental processes, including planar cell polarity and directed cell rearrangements. Here we demonstrate that the dual-specificity transcriptional repressor Kaiso, first identified in association with p120-catenin, is required for Xenopus gastrulation movements. In addition, depletion of xKaiso results in increased expression of the non-canonical xWnt11, which contributes to the xKaiso knockdown phenotype as it is significantly rescued by dominant-negative Wnt11. We further demonstrate that xWnt11 is a direct gene target of xKaiso and that p120-catenin association relieves xKaiso repression in vivo. Our results indicate that p120-catenin and Kaiso are essential components of a new developmental gene regulatory pathway that controls vertebrate morphogenesis."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncb1191"xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncb1191"xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Ji H."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Ji H."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Daniel J.M."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Daniel J.M."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Kim S.-W."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Kim S.-W."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Sater A.K."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Sater A.K."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "McCrea P.D."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "McCrea P.D."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Park J.-I."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Park J.-I."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Otchere A.A."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Otchere A.A."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Spring C.M."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/author | "Spring C.M."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/name | "Nat. Cell Biol."xsd:string |
http://purl.uniprot.org/citations/15543138 | http://purl.uniprot.org/core/name | "Nat. Cell Biol."xsd:string |