| http://purl.uniprot.org/citations/15563606 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15563606 | http://www.w3.org/2000/01/rdf-schema#comment | "Kinesin-1 is a heterotetramer composed of kinesin heavy chain (KHC) and kinesin light chain (KLC). The Caenorhabditis elegans genome has a single KHC, encoded by the unc-116 gene, and two KLCs, encoded by the klc-1 and klc-2 genes. We show here that UNC-116/KHC and KLC-2 form a complex orthologous to conventional kinesin-1. KLC-2 also binds UNC-16, the C. elegans JIP3/JSAP1 JNK-signaling scaffold protein, and the UNC-14 RUN domain protein. The localization of UNC-16 and UNC-14 depends on kinesin-1 (UNC-116 and KLC-2). Furthermore, mutations in unc-16, klc-2, unc-116, and unc-14 all alter the localization of cargos containing synaptic vesicle markers. Double mutant analysis is consistent with these four genes functioning in the same pathway. Our data support a model whereby UNC-16 and UNC-14 function together as kinesin-1 cargos and regulators for the transport or localization of synaptic vesicle components."xsd:string |
| http://purl.uniprot.org/citations/15563606 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e04-07-0553"xsd:string |
| http://purl.uniprot.org/citations/15563606 | http://purl.uniprot.org/core/author | "Jin Y."xsd:string |
| http://purl.uniprot.org/citations/15563606 | http://purl.uniprot.org/core/author | "Matsumoto K."xsd:string |
| http://purl.uniprot.org/citations/15563606 | http://purl.uniprot.org/core/author | "Sakamoto R."xsd:string |
| http://purl.uniprot.org/citations/15563606 | http://purl.uniprot.org/core/author | "Hisamoto N."xsd:string |
| http://purl.uniprot.org/citations/15563606 | http://purl.uniprot.org/core/author | "Brown H.M."xsd:string |
| http://purl.uniprot.org/citations/15563606 | http://purl.uniprot.org/core/author | "Byrd D.T."xsd:string |
| http://purl.uniprot.org/citations/15563606 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15563606 | http://purl.uniprot.org/core/name | "Mol Biol Cell"xsd:string |
| http://purl.uniprot.org/citations/15563606 | http://purl.uniprot.org/core/pages | "483-496"xsd:string |
| http://purl.uniprot.org/citations/15563606 | http://purl.uniprot.org/core/title | "The Caenorhabditis elegans UNC-14 RUN domain protein binds to the kinesin-1 and UNC-16 complex and regulates synaptic vesicle localization."xsd:string |
| http://purl.uniprot.org/citations/15563606 | http://purl.uniprot.org/core/volume | "16"xsd:string |
| http://purl.uniprot.org/citations/15563606 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15563606 |
| http://purl.uniprot.org/citations/15563606 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15563606 |
| http://purl.uniprot.org/uniprot/P34609#attribution-91F25B0A68315FDB262CB64D98364D45 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15563606 |
| http://purl.uniprot.org/uniprot/P34540#attribution-485F267FB820FCA248C6A58714D5D0D4 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15563606 |
| http://purl.uniprot.org/uniprot/P34540#attribution-91F25B0A68315FDB262CB64D98364D45 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15563606 |
| http://purl.uniprot.org/uniprot/P34540#attribution-E0676C5D61B0DBB4D4DF45523AD498C1 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15563606 |
| http://purl.uniprot.org/uniprot/P46822#attribution-485F267FB820FCA248C6A58714D5D0D4 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15563606 |
| http://purl.uniprot.org/uniprot/P46822#attribution-91F25B0A68315FDB262CB64D98364D45 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15563606 |
| http://purl.uniprot.org/uniprot/P46822#attribution-E0676C5D61B0DBB4D4DF45523AD498C1 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15563606 |
| http://purl.uniprot.org/uniprot/G5ECQ1#attribution-4CB2CCFC1538EE7F09B47B36440CC6E9 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15563606 |
| http://purl.uniprot.org/uniprot/G5ECQ1#attribution-91F25B0A68315FDB262CB64D98364D45 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15563606 |