| http://purl.uniprot.org/citations/15578261 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15578261 | http://www.w3.org/2000/01/rdf-schema#comment | "HLA-G is a non-classical HLA class Ib molecule primarily expressed in trophoblast cells, and is thought to play a key role in the induction of materno-fetal tolerance during pregnancy. In addition, the HLA-G gene provides a suitable leader sequence peptide capable of binding to HLA-E. However, the existence of placentas homozygous for the HLA-G*0105N null allele suggests that HLA-G1 might not be essential for fetal survival. To investigate whether expression of the HLA-G*0105N allele supports HLA-E cell surface expression, we transfected the HLA-G*0105N gene into JAR trophoblast cells. Flow cytometry analysis showed that HLA-G*0105N-transfected cells express surface HLA-E to a similar extent as the unmutated HLA-G gene, whereas HLA-G1 cell surface expression was undetectable. Using the NKL cell line in a standard (51)Cr release assay, the HLA-E molecules were found to inhibit natural killer lysis, through a mechanism partially dependent on CD94/NKG2A-mediated recognition."xsd:string |
| http://purl.uniprot.org/citations/15578261 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00251-004-0733-7"xsd:string |
| http://purl.uniprot.org/citations/15578261 | http://purl.uniprot.org/core/author | "Lenfant F."xsd:string |
| http://purl.uniprot.org/citations/15578261 | http://purl.uniprot.org/core/author | "Le Bouteiller P."xsd:string |
| http://purl.uniprot.org/citations/15578261 | http://purl.uniprot.org/core/author | "Legrand-Abravanel F."xsd:string |
| http://purl.uniprot.org/citations/15578261 | http://purl.uniprot.org/core/author | "Pizzato N."xsd:string |
| http://purl.uniprot.org/citations/15578261 | http://purl.uniprot.org/core/author | "Sala F.G."xsd:string |
| http://purl.uniprot.org/citations/15578261 | http://purl.uniprot.org/core/author | "Del Moral P.M."xsd:string |
| http://purl.uniprot.org/citations/15578261 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15578261 | http://purl.uniprot.org/core/name | "Immunogenetics"xsd:string |
| http://purl.uniprot.org/citations/15578261 | http://purl.uniprot.org/core/pages | "617-624"xsd:string |
| http://purl.uniprot.org/citations/15578261 | http://purl.uniprot.org/core/title | "The HLA-G*0105N null allele induces cell surface expression of HLA-E molecule and promotes CD94/NKG2A-mediated recognition in JAR choriocarcinoma cell line."xsd:string |
| http://purl.uniprot.org/citations/15578261 | http://purl.uniprot.org/core/volume | "56"xsd:string |
| http://purl.uniprot.org/citations/15578261 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15578261 |
| http://purl.uniprot.org/citations/15578261 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15578261 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9X9-mappedCitation-15578261 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15578261 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y0-mappedCitation-15578261 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15578261 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y1-mappedCitation-15578261 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15578261 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y2-mappedCitation-15578261 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15578261 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y3-mappedCitation-15578261 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15578261 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y6-mappedCitation-15578261 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15578261 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Z1-mappedCitation-15578261 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15578261 |
| http://purl.uniprot.org/uniprot/#_A0A0H4LTX5-mappedCitation-15578261 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15578261 |
| http://purl.uniprot.org/uniprot/#_A0A0H4LTX9-mappedCitation-15578261 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15578261 |