| http://purl.uniprot.org/citations/15582780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15582780 | http://www.w3.org/2000/01/rdf-schema#comment | "Nuclear translocation, driven by the motility apparatus consisting of the cytoplasmic dynein motor and microtubules, is essential for cell migration during embryonic development. Bicaudal-D (Bic-D), an evolutionarily conserved dynein-interacting protein, is required for developmental control of nuclear migration in Drosophila. Nothing is known about the signaling events that coordinate the function of Bic-D and dynein during development. Here, we show that Misshapen (Msn), the fly homolog of the vertebrate Nck-interacting kinase is a component of a novel signaling pathway that regulates photoreceptor (R-cell) nuclear migration in the developing Drosophila compound eye. Msn, like Bic-D, is required for the apical migration of differentiating R-cell precursor nuclei. msn displays strong genetic interaction with Bic-D. Biochemical studies demonstrate that Msn increases the phosphorylation of Bic-D, which appears to be necessary for the apical accumulation of both Bic-D and dynein in developing R-cell precursor cells. We propose that Msn functions together with Bic-D to regulate the apical localization of dynein in generating directed nuclear migration within differentiating R-cell precursor cells."xsd:string |
| http://purl.uniprot.org/citations/15582780 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.mod.2004.08.005"xsd:string |
| http://purl.uniprot.org/citations/15582780 | http://purl.uniprot.org/core/author | "Rao Y."xsd:string |
| http://purl.uniprot.org/citations/15582780 | http://purl.uniprot.org/core/author | "Ruan W."xsd:string |
| http://purl.uniprot.org/citations/15582780 | http://purl.uniprot.org/core/author | "Suter B."xsd:string |
| http://purl.uniprot.org/citations/15582780 | http://purl.uniprot.org/core/author | "Hien Vuong D."xsd:string |
| http://purl.uniprot.org/citations/15582780 | http://purl.uniprot.org/core/author | "Houalla T."xsd:string |
| http://purl.uniprot.org/citations/15582780 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15582780 | http://purl.uniprot.org/core/name | "Mech Dev"xsd:string |
| http://purl.uniprot.org/citations/15582780 | http://purl.uniprot.org/core/pages | "97-108"xsd:string |
| http://purl.uniprot.org/citations/15582780 | http://purl.uniprot.org/core/title | "The Ste20-like kinase misshapen functions together with Bicaudal-D and dynein in driving nuclear migration in the developing drosophila eye."xsd:string |
| http://purl.uniprot.org/citations/15582780 | http://purl.uniprot.org/core/volume | "122"xsd:string |
| http://purl.uniprot.org/citations/15582780 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15582780 |
| http://purl.uniprot.org/citations/15582780 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15582780 |
| http://purl.uniprot.org/uniprot/Q7KV90#attribution-E65972F65F69805474CB1553FB1D875B | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15582780 |
| http://purl.uniprot.org/uniprot/Q7KV88#attribution-E65972F65F69805474CB1553FB1D875B | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15582780 |
| http://purl.uniprot.org/uniprot/M9PBJ7#attribution-E65972F65F69805474CB1553FB1D875B | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15582780 |
| http://purl.uniprot.org/uniprot/M9PH19#attribution-E65972F65F69805474CB1553FB1D875B | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15582780 |
| http://purl.uniprot.org/uniprot/Q7KV89#attribution-E65972F65F69805474CB1553FB1D875B | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15582780 |
| http://purl.uniprot.org/uniprot/Q9W002#attribution-E65972F65F69805474CB1553FB1D875B | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15582780 |
| http://purl.uniprot.org/uniprot/#_E1JHD6-mappedCitation-15582780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15582780 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K812-mappedCitation-15582780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15582780 |
| http://purl.uniprot.org/uniprot/#_A8JNH1-mappedCitation-15582780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15582780 |
| http://purl.uniprot.org/uniprot/#_A8JNH2-mappedCitation-15582780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15582780 |