http://purl.uniprot.org/citations/15603876 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15603876 | http://www.w3.org/2000/01/rdf-schema#comment | "We evaluated human leukocyte antigen (HLA)-DRB1 and -DQB1 alleles as genetic markers for Vogt-Koyanagi-Harada (VKH) disease in Mestizo patients in Southern California. Mestizo individuals with VKH disease (n = 29) at two institutions were evaluated. Typing of HLA-DRB1 and DQB1 genes was performed using DNA-based techniques. Gene frequencies were compared to Mestizo individuals living in Southern California. All patients had HLA-DRB1*01, DRB1*04, DQB1*03 or DQB1*05, or a combination of these genes. The gene frequency of combined HLA-DR4 alleles was increased when compared to controls. The frequencies of HLA-DRB1*0404 and DRB1*0407 were increased compared to controls, but were not significant after Bonferroni correction. Three patients had the HLA-DRB1*0410 allele; this allele was not found in controls. All HLA-DRB1*01 positive patients had the DRB1*0102 subtype. No HLA-DQB1 allele was significantly increased compared to controls. This study is the first to identify a possible association between HLA-DRB1*0404 and VKH disease, as well as to find DRB1*0102 and DRB1*0410 in Mestizo patients."xsd:string |
http://purl.uniprot.org/citations/15603876 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.humimm.2004.07.236"xsd:string |
http://purl.uniprot.org/citations/15603876 | http://purl.uniprot.org/core/author | "Rao N.A."xsd:string |
http://purl.uniprot.org/citations/15603876 | http://purl.uniprot.org/core/author | "Park M.S."xsd:string |
http://purl.uniprot.org/citations/15603876 | http://purl.uniprot.org/core/author | "Reed E.F."xsd:string |
http://purl.uniprot.org/citations/15603876 | http://purl.uniprot.org/core/author | "Rajalingam R."xsd:string |
http://purl.uniprot.org/citations/15603876 | http://purl.uniprot.org/core/author | "Holland G.N."xsd:string |
http://purl.uniprot.org/citations/15603876 | http://purl.uniprot.org/core/author | "Levinson R.D."xsd:string |
http://purl.uniprot.org/citations/15603876 | http://purl.uniprot.org/core/author | "See R.F."xsd:string |
http://purl.uniprot.org/citations/15603876 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15603876 | http://purl.uniprot.org/core/name | "Hum Immunol"xsd:string |
http://purl.uniprot.org/citations/15603876 | http://purl.uniprot.org/core/pages | "1477-1482"xsd:string |
http://purl.uniprot.org/citations/15603876 | http://purl.uniprot.org/core/title | "HLA-DRB1 and -DQB1 alleles in mestizo patients with Vogt-Koyanagi-Harada's disease in Southern California."xsd:string |
http://purl.uniprot.org/citations/15603876 | http://purl.uniprot.org/core/volume | "65"xsd:string |
http://purl.uniprot.org/citations/15603876 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15603876 |
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