http://purl.uniprot.org/citations/15620693 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15620693 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15620693 | http://www.w3.org/2000/01/rdf-schema#comment | "A new member of the UDP-N-acetylglucosamine: beta-galactose beta1,3-N-acetylglucosaminyltransferase (beta3Gn-T) family having the beta3-glycosyltransferase motifs was identified using an in silico method. This novel beta3Gn-T was cloned from a human colon cancer cell line and named beta3Gn-T8 based on its position in a phylogenetic tree and enzymatic activity. Beta3Gn-T8 transfers GlcNAc to the non-reducing terminus of the Galbeta1-4GlcNAc of tetraantennary N-glycan in vitro. HCT15 cells transfected with beta3Gn-T8 cDNA showed an increase in reactivity to both LEA and PHA-L4 in a flow cytometric analysis. These results indicated that beta3Gn-T8 is involved in the biosynthesis of poly-N-acetyllactosamine chains on tetraantennary (beta1,6-branched) N-glycan. In most of the colorectal cancer tissues examined, the level of beta3Gn-T8 transcript was significantly higher than in normal tissue. Beta3Gn-T8 could be an enzyme involved in the synthesis of poly-N-acetyllactosamine on beta1-6 branched N-glycans in colon cancer."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2004.11.037"xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2004.11.037"xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Iwai T."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Iwai T."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Ishida H."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Ishida H."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Kudo T."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Kudo T."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Sato T."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Sato T."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Tanaka N."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Tanaka N."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Sakai T."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Sakai T."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Gotoh M."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Gotoh M."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Hiruma T."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Hiruma T."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Inaba N."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Inaba N."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Narimatsu H."xsd:string |
http://purl.uniprot.org/citations/15620693 | http://purl.uniprot.org/core/author | "Narimatsu H."xsd:string |