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http://purl.uniprot.org/citations/15629922http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15629922http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15629922http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Citation
http://purl.uniprot.org/citations/15629922http://www.w3.org/2000/01/rdf-schema#comment"The gene prmC, encoding the putative S-adenosyl-L-methionine (AdoMet)-dependent methyltransferase (MTase) of release factors (RFs) of the obligate intracellular pathogen Chlamydia trachomatis, was functionally analyzed. Chlamydial PrmC expression suppresses the growth defect of a prmC knockout strain of Escherichia coli K-12, suggesting an interaction of chlamydial PrmC with E. coli RFs in vivo. In vivo methylation assays carried out with recombinant PrmC and RFs of chlamydial origin demonstrated that PrmC methylates RFs within the tryptic fragment containing the universally conserved sequence motif Gly-Gly-Gln. This is consistent with the enzymatic properties of PrmC of E. coli origin. We conclude that C. trachomatis PrmC functions as an N5-glutamine AdoMet-dependent MTase, involved in methylation of RFs."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.org/dc/terms/identifier"doi:10.1128/jb.187.2.507-511.2005"xsd:string
http://purl.uniprot.org/citations/15629922http://purl.org/dc/terms/identifier"doi:10.1128/jb.187.2.507-511.2005"xsd:string
http://purl.uniprot.org/citations/15629922http://purl.org/dc/terms/identifier"doi:10.1128/JB.187.2.507-511.2005"xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/author"Pannekoek Y."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/author"Pannekoek Y."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/author"van der Ende A."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/author"van der Ende A."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/author"Buckingham R.H."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/author"Buckingham R.H."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/author"Heurgue-Hamard V."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/author"Heurgue-Hamard V."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/author"Langerak A.A."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/author"Langerak A.A."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/author"Speijer D."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/author"Speijer D."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/name"J. Bacteriol."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/name"J. Bacteriol."xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/pages"507-511"xsd:string
http://purl.uniprot.org/citations/15629922http://purl.uniprot.org/core/pages"507-511"xsd:string