| http://purl.uniprot.org/citations/15640798 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15640798 | http://www.w3.org/2000/01/rdf-schema#comment | "Diverse protocadherin-alpha genes (Pcdha, also called cadherin-related neuronal receptor or CNR) are expressed in the vertebrate brain. Their genomic organization involves multiple variable exons and a set of constant exons, similar to the immunoglobulin (Ig) and T-cell receptor (TCR) genes. This diversity can be used to distinguish neurons. Using polymorphisms that distinguish the C57BL/6 and MSM mouse strains, we analyzed the allelic expression of the Pcdha gene cluster in individual neurons. Single-cell analysis of Purkinje cells using multiple RT-PCR reactions showed the monoallelic and combinatorial expression of each variable exon in the Pcdha genes. This report is the first description to our knowledge of the allelic expression of a diversified receptor family in the central nervous system. The allelic and combinatorial expression of distinct variable exons of the Pcdha genes is a potential mechanism for specifying neuron identity in the brain."xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng1500"xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/author | "Hamada S."xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/author | "Koide T."xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/author | "Hirayama T."xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/author | "Yagi T."xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/author | "Sasaki A."xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/author | "Taguchi Y."xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/author | "Hirabayashi T."xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/author | "Kakazu N."xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/author | "Esumi S."xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/author | "Kitsukawa T."xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/name | "Nat Genet"xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/pages | "171-176"xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/title | "Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons."xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://purl.uniprot.org/core/volume | "37"xsd:string |
| http://purl.uniprot.org/citations/15640798 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15640798 |
| http://purl.uniprot.org/citations/15640798 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15640798 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YX38-mappedCitation-15640798 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15640798 |
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| http://purl.uniprot.org/uniprot/#_O88689-mappedCitation-15640798 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15640798 |