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http://purl.uniprot.org/citations/15644333http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15644333http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15644333http://www.w3.org/2000/01/rdf-schema#comment"CCAAT/enhancer-binding protein beta (C/EBP beta) is expressed early during the adipocyte differentiation program and plays an important role in this process. In an attempt to identify novel proteins that interact with C/EBP beta, we performed a yeast two-hybrid screen with a preadipocyte cDNA library and identified a new co-regulator, delta-interacting protein A (DIPA). DIPA mRNA is expressed during adipocyte differentiation of clonal cell lines. DIPA interacts with C/EBP beta and -delta proteins in intact cells and inhibits their transcriptional activity but not that of C/EBP alpha. Stable overexpression of DIPA in preadipocytes partially inhibits adipocyte differentiation, whereas its gene silencing enhances this process. DIPA and C/EBP beta co-localize in the nucleus, and overexpression of DIPA in preadipocytes results in a partial inhibition of the mitotic clonal expansion which is critical for differentiation. Thus, DIPA is a novel partner of C/EBP beta that down-regulates early events of adipogenesis."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.org/dc/terms/identifier"doi:10.1074/jbc.m411741200"xsd:string
http://purl.uniprot.org/citations/15644333http://purl.org/dc/terms/identifier"doi:10.1074/jbc.m411741200"xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Kristiansen K."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Kristiansen K."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Ailhaud G."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Ailhaud G."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Amri E.-Z."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Amri E.-Z."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Bezy O."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Bezy O."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Elabd C."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Elabd C."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Dani C."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Dani C."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Cochet O."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Cochet O."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Petersen R.K."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/author"Petersen R.K."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/15644333http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string