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http://purl.uniprot.org/citations/15649465http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15649465http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15649465http://www.w3.org/2000/01/rdf-schema#comment"The Caenorhabditis elegans vulva is comprised of highly similar anterior and posterior halves that are arranged in a mirror symmetric pattern. The cell lineages that form each half of the vulva are identical, except that they occur in opposite orientations with respect to the anterior/posterior axis. We show that most vulval cell divisions produce sister cells that have asymmetric levels of POP-1 and that the asymmetry has opposite orientations in the two halves of the vulva. We demonstrate that lin-17 (Frizzled type Wnt receptor) and lin-18 (Ryk) regulate the pattern of POP-1 localization and cell type specification in the posterior half of the vulva. In the absence of lin-17 and lin-18, posterior lineages are reversed and resemble anterior lineages. These experiments suggest that Wnt signaling pathways reorient cell lineages in the posterior half of the vulva from a default orientation displayed in the anterior half of the vulva."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.org/dc/terms/identifier"doi:10.1016/j.ydbio.2004.10.020"xsd:string
http://purl.uniprot.org/citations/15649465http://purl.org/dc/terms/identifier"doi:10.1016/j.ydbio.2004.10.020"xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/author"Inoue T."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/author"Inoue T."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/author"Hill R.J."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/author"Hill R.J."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/author"Priess J.R."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/author"Priess J.R."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/author"Deshpande R."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/author"Deshpande R."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/name"Dev. Biol."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/name"Dev. Biol."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/pages"118-129"xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/pages"118-129"xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/title"lin-17/Frizzled and lin-18 regulate POP-1/TCF-1 localization and cell type specification during C. elegans vulval development."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/title"lin-17/Frizzled and lin-18 regulate POP-1/TCF-1 localization and cell type specification during C. elegans vulval development."xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/volume"278"xsd:string
http://purl.uniprot.org/citations/15649465http://purl.uniprot.org/core/volume"278"xsd:string
http://purl.uniprot.org/citations/15649465http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15649465
http://purl.uniprot.org/citations/15649465http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15649465