DESCRIBE <http://purl.uniprot.org/citations/15656374>

Subject	Predicate	Object
http://purl.uniprot.org/citations/15656374	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15656374	http://www.w3.org/2000/01/rdf-schema#comment	" Purpose To investigate the expression of p53, MDM2 and Ref1 gene in cultured retina neurons of SD rats treated with Vitamin B1 and (or) elevated pressure. Methods The retinal neuron of postnatal SD rats were cultured in vivo, the elevated pressure was produced after 7 days, and the total RNA was extracted after another 2 days, expression of p53, MDM2 and Ref1 gene were analyzed with RT-PCR. Results The expression level of p53 and MDM2 gene were increased in elevated pressure group, normal with Ref1 gene expression. But the expression of p53 and MDM2 gene were decreased significantly in elevated pressure group treated with vitamine B1 compare to the elevated group. Conclusion Apoptosis seem to be a mechanism of cell death in retinal neurons of SD rats with elevated pressure.Vitamine B1 have protect effects against elevated pressure."xsd:string
http://purl.uniprot.org/citations/15656374	http://purl.uniprot.org/core/author	"Guo Y."xsd:string
http://purl.uniprot.org/citations/15656374	http://purl.uniprot.org/core/author	"Ge J."xsd:string
http://purl.uniprot.org/citations/15656374	http://purl.uniprot.org/core/author	"Liu H."xsd:string
http://purl.uniprot.org/citations/15656374	http://purl.uniprot.org/core/author	"Shen H."xsd:string
http://purl.uniprot.org/citations/15656374	http://purl.uniprot.org/core/author	"Yang Z."xsd:string
http://purl.uniprot.org/citations/15656374	http://purl.uniprot.org/core/author	"Yin W."xsd:string
http://purl.uniprot.org/citations/15656374	http://purl.uniprot.org/core/date	"2004"xsd:gYear
http://purl.uniprot.org/citations/15656374	http://purl.uniprot.org/core/name	"Yan Ke Xue Bao (Hong Kong)"xsd:string
http://purl.uniprot.org/citations/15656374	http://purl.uniprot.org/core/pages	"259-263"xsd:string
http://purl.uniprot.org/citations/15656374	http://purl.uniprot.org/core/title	"[The expression of p53, MDM2 and Ref1 gene in cultured retina neurons of SD rats treated with vitamin B1 and/or elevated pressure]."xsd:string
http://purl.uniprot.org/citations/15656374	http://purl.uniprot.org/core/volume	"20"xsd:string
http://purl.uniprot.org/citations/15656374	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/15656374
http://purl.uniprot.org/citations/15656374	http://xmlns.com/foaf/0.1/primaryTopicOf	https://pubmed.ncbi.nlm.nih.gov/15656374
http://purl.uniprot.org/uniprot/D3ZVH5#attribution-5A9FE930796E7F0237E0D7912AD8F441	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/15656374
http://purl.uniprot.org/uniprot/A0A0G2JVC1#attribution-5A9FE930796E7F0237E0D7912AD8F441	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/15656374
http://purl.uniprot.org/uniprot/A0A8I6G5V3#attribution-5A9FE930796E7F0237E0D7912AD8F441	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/15656374
http://purl.uniprot.org/uniprot/A0A8I6GK47#attribution-5A9FE930796E7F0237E0D7912AD8F441	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/15656374
http://purl.uniprot.org/uniprot/A6IGT1#attribution-5A9FE930796E7F0237E0D7912AD8F441	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/15656374
http://purl.uniprot.org/uniprot/#_A0A0G2JVC1-mappedCitation-15656374	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/15656374
http://purl.uniprot.org/uniprot/#_D3ZVH5-mappedCitation-15656374	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/15656374
http://purl.uniprot.org/uniprot/#_A0A8I6G5V3-mappedCitation-15656374	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/15656374
http://purl.uniprot.org/uniprot/#_A0A8I6GK47-mappedCitation-15656374	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/15656374
http://purl.uniprot.org/uniprot/A0A0G2JVC1	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/15656374