http://purl.uniprot.org/citations/1566087 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1566087 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1566087 | http://www.w3.org/2000/01/rdf-schema#comment | "The proto-oncogene c-abl encodes a protein tyrosine kinase that is localized in the cytoplasm and the nucleus. The large carboxyl-terminal segment of c-Abl was found to contain a DNA-binding domain that was necessary for the association of c-Abl with chromatin. The DNA-binding activity of c-Abl was lost during mitosis when the carboxyl-terminal segment became phosphorylated. In vitro phosphorylation of the DNA-binding domain by cdc2 kinase abolished DNA binding. Homozygous mutant mice expressing a c-Abl tyrosine kinase without the DNA-binding domain have been reported to die of multiple defects at birth. Thus, binding of the c-Abl tyrosine kinase to DNA may be essential to its biological function."xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.256.5055.382"xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.256.5055.382"xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/author | "Wang J.Y."xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/author | "Wang J.Y."xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/author | "Kipreos E.T."xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/author | "Kipreos E.T."xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/pages | "382-385"xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/pages | "382-385"xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/title | "Cell cycle-regulated binding of c-Abl tyrosine kinase to DNA."xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/title | "Cell cycle-regulated binding of c-Abl tyrosine kinase to DNA."xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/volume | "256"xsd:string |
http://purl.uniprot.org/citations/1566087 | http://purl.uniprot.org/core/volume | "256"xsd:string |
http://purl.uniprot.org/citations/1566087 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1566087 |
http://purl.uniprot.org/citations/1566087 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1566087 |
http://purl.uniprot.org/citations/1566087 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1566087 |
http://purl.uniprot.org/citations/1566087 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1566087 |
http://purl.uniprot.org/uniprot/P00520 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1566087 |
http://purl.uniprot.org/uniprot/P00520#attribution-1E5186A677D2A5CE3CBA1274F4EF2DEA | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1566087 |