| http://purl.uniprot.org/citations/15671017 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15671017 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15671017 | http://www.w3.org/2000/01/rdf-schema#comment | "Cyclin-dependent kinase 2 (cdk2) activation requires phosphorylation of Thr160 and dissociation from cyclin A. The T-loop of cdk2 contains a regulatory phosphorylation site at Thr160. An interaction between cdc-associated phosphatase (KAP) and cdk2 compromises the interaction between cdk2 and cyclin A, which permits access of KAP, a Thr160-directed phosphatase, to its substrate, cdk2. We have reported that KAP is bound and activated by a nuclear membrane protein, HTm4. Here, we present in vitro data showing the direct interaction between the HTm4 C terminus and KAP Tyr141. We show that this interaction not only facilitates access of KAP to Thr160 and accelerates KAP kinetics, but also forces exclusion of cyclin A from the KAP.cdk2 complex."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m413437200"xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m413437200"xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Yang X."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Yang X."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Shirakawa T."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Shirakawa T."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Yano Y."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Yano Y."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Moriyama K."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Moriyama K."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Shiroishi M."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Shiroishi M."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Chinami M."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Chinami M."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Salahuddin S."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Salahuddin S."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Adra C.N."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Adra C.N."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Turner H."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/author | "Turner H."xsd:string |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15671017 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |