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http://purl.uniprot.org/citations/15690487http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15690487http://www.w3.org/2000/01/rdf-schema#comment"The central neuropeptide Y (NPY) Y1 receptor (Y1-R) system has been implicated in feeding, endocrine, and autonomic regulation. In the present study, we systematically examined the brain distribution of Y1-R mRNA in rodents by using radioisotopic in situ hybridization histochemistry (ISHH) with a novel sensitive cRNA probe. Within the rat hypothalamus, Y1-R-specific hybridization was observed in the anteroventral periventricular, ventromedial preoptic, suprachiasmatic, paraventricular (PVH), dorsomedial, ventromedial, arcuate, and mamillary nuclei. In the rat, Y1-R mRNA expression was also seen in the subfornical organ, anterior hypothalamic area, dorsal hypothalamic area, and in the lateral hypothalamic area. In addition, Y1-R hybridization was evident in several extrahypothalamic forebrain and hindbrain sites involved in feeding and/or autonomic regulation in the rat. A similar distribution pattern of Y1-R mRNA was observed in the mouse brain. Moreover, by using a transgenic mouse line expressing green fluorescent protein under the control of the melanocortin-4 receptor (MC4-R) promoter, we observed Y1-R mRNA expression in MC4-R-positive cells in several brain sites such as the PVH and central nucleus of the amygdala. Additionally, dual-label ISHH demonstrated that hypophysiotropic PVH cells coexpress Y1-R and pro-thyrotropin-releasing hormone mRNAs in the rat. These observations are consistent with the proposed roles of the central NPY/Y1-R system in energy homeostasis."xsd:string
http://purl.uniprot.org/citations/15690487http://purl.org/dc/terms/identifier"doi:10.1002/cne.20432"xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/author"Liu H."xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/author"Elmquist J.K."xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/author"Friedman J.M."xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/author"Lee C.E."xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/author"Kishi T."xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/author"Hollenberg A.N."xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/author"Lopez M.E."xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/author"Choi B.J."xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/author"Aschkenasi C.J."xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/name"J Comp Neurol"xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/pages"217-243"xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/title"Neuropeptide Y Y1 receptor mRNA in rodent brain: distribution and colocalization with melanocortin-4 receptor."xsd:string
http://purl.uniprot.org/citations/15690487http://purl.uniprot.org/core/volume"482"xsd:string
http://purl.uniprot.org/citations/15690487http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15690487
http://purl.uniprot.org/citations/15690487http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15690487
http://purl.uniprot.org/uniprot/#_A6KFL5-mappedCitation-15690487http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15690487
http://purl.uniprot.org/uniprot/#_P21555-mappedCitation-15690487http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15690487
http://purl.uniprot.org/uniprot/#_G3V7T1-mappedCitation-15690487http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15690487
http://purl.uniprot.org/uniprot/#_Q04573-mappedCitation-15690487http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15690487
http://purl.uniprot.org/uniprot/#_Q3V1K5-mappedCitation-15690487http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15690487
http://purl.uniprot.org/uniprot/#_Q5FVH5-mappedCitation-15690487http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15690487