| http://purl.uniprot.org/citations/15694306 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15694306 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15694306 | http://www.w3.org/2000/01/rdf-schema#comment | "Telomeres are essential for the protection of chromosomes against nucleases and recombinases and for the addition of G+T-rich simple sequence by the ribonucleoprotein reverse transcriptase telomerase . Telomere size instability and loss of telomerase activity in somatic cells is strongly associated with both oncogenesis and aging . Yet, an understanding of the mechanisms that maintain telomere size and structure during meiosis is still in its infancy . We have investigated the stability of single elongated telomeres during yeast meiosis. We find that elongated telomeres undergo high rates of precise deletion to wild-type telomere size via an intrachromatid pathway that shares properties with mitotic telomere rapid deletion (TRD). Loss of Ndj1p, a telomeric protein necessary for meiotic bouquet structure formation , confers a severe reduction in deletion rates. Return-to-growth (RTG) experiments suggest that deletion occurs at or near the period of meiotic recombination in NDJ1/NDJ1, but not in ndj1Delta/ndj1Delta diploids . We propose that Ndj1p facilitates deletion by promoting telomeric interactions during meiosis, resulting in an effective increase in the concentration of limiting factors for deletion."xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cub.2005.01.039"xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cub.2005.01.039"xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/author | "Jia D."xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/author | "Jia D."xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/author | "Lustig A.J."xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/author | "Lustig A.J."xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/author | "Joseph I."xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/author | "Joseph I."xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/name | "Curr. Biol."xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/name | "Curr. Biol."xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/pages | "231-237"xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/pages | "231-237"xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/title | "Ndj1p-dependent epigenetic resetting of telomere size in yeast meiosis."xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/title | "Ndj1p-dependent epigenetic resetting of telomere size in yeast meiosis."xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/volume | "15"xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://purl.uniprot.org/core/volume | "15"xsd:string |
| http://purl.uniprot.org/citations/15694306 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15694306 |
| http://purl.uniprot.org/citations/15694306 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15694306 |
| http://purl.uniprot.org/citations/15694306 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15694306 |
| http://purl.uniprot.org/citations/15694306 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15694306 |