http://purl.uniprot.org/citations/15696166 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15696166 | http://www.w3.org/2000/01/rdf-schema#comment | "Transcriptional repression of methylated genes can be mediated by the methyl-CpG binding protein MeCP2. Here we show that human Brahma (Brm), a catalytic component of the SWI/SNF-related chromatin-remodeling complex, associates with MeCP2 in vivo and is functionally linked with repression. We used a number of different molecular approaches and chromatin immunoprecipitation strategies to show a unique cooperation between Brm, BAF57 and MeCP2. We show that Brm and MeCP2 assembly on chromatin occurs on methylated genes in cancer and the gene FMR1 in fragile X syndrome. These experimental findings identify a new role for SWI/SNF in gene repression by MeCP2."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng1516"xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/author | "Pal S."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/author | "Wang L."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/author | "Sif S."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/author | "Baker E.K."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/author | "Craig J.M."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/author | "Jones P.L."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/author | "El-Osta A."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/author | "Bassal S."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/author | "Brasacchio D."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/author | "Chow M.Z."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/author | "Harikrishnan K.N."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/name | "Nat Genet"xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/pages | "254-264"xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/title | "Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing."xsd:string |
http://purl.uniprot.org/citations/15696166 | http://purl.uniprot.org/core/volume | "37"xsd:string |
http://purl.uniprot.org/citations/15696166 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15696166 |
http://purl.uniprot.org/citations/15696166 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15696166 |
http://purl.uniprot.org/uniprot/#_D3Z7U4-mappedCitation-15696166 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15696166 |
http://purl.uniprot.org/uniprot/#_E9QAB8-mappedCitation-15696166 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15696166 |
http://purl.uniprot.org/uniprot/#_D3YY81-mappedCitation-15696166 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15696166 |
http://purl.uniprot.org/uniprot/#_A0A140LHE2-mappedCitation-15696166 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15696166 |