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http://purl.uniprot.org/citations/15713222http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15713222http://www.w3.org/2000/01/rdf-schema#comment"In the current study, we investigated human leukocyte antigen (HLA) class II alleles in Caucasian women with primary biliary cirrhosis (PBC), a disease that preferentially affects women. Alleles of DRB1, DQA1, and DQB1 were determined by DNA-based HLA typing for women with PBC (n = 72) and healthy women (n = 381). All study subjects were Caucasian. HLA DRB1*08 was significantly increased in women with PBC compared to healthy women. The increase was primarily due to the DRB1*0801 allele, also the most common DRB1*08 allele among controls. DQB1*04 and DQA1*0401 were significantly increased. DRB1*1501, DQA1*0102, and DQB1*0602 were associated with decreased risk. Analyses conducted comparing parous women with PBC to parous healthy women (n = 68 and n = 282, respectively) yielded similar significant results. Although the DRB1*08-DQA1*0401-DQB1*04 haplotype was significantly associated with PBC, consistent with other studies, this haplotype nevertheless represented only 19% (14/72) of all PBC patients and can account for only a minority of the risk of PBC."xsd:string
http://purl.uniprot.org/citations/15713222http://purl.org/dc/terms/identifier"doi:10.1111/j.1399-0039.2005.00351.x"xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/author"Porter A.J."xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/author"Galloway D.A."xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/author"Stevens A.M."xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/author"Pang J.M."xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/author"Nelson J.L."xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/author"McDonnell W.M."xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/author"Loubiere L.S."xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/author"Mullarkey M.E."xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/author"Brackensick J.A."xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/name"Tissue Antigens"xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/pages"199-205"xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/title"Human leukocyte antigen class II alleles in Caucasian women with primary biliary cirrhosis."xsd:string
http://purl.uniprot.org/citations/15713222http://purl.uniprot.org/core/volume"65"xsd:string
http://purl.uniprot.org/citations/15713222http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15713222
http://purl.uniprot.org/citations/15713222http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15713222
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-15713222http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15713222
http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-15713222http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15713222
http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-15713222http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15713222
http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-15713222http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15713222
http://purl.uniprot.org/uniprot/#_A0A0E3DC99-mappedCitation-15713222http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15713222
http://purl.uniprot.org/uniprot/#_A0A076L4M5-mappedCitation-15713222http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15713222