http://purl.uniprot.org/citations/15716360 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15716360 | http://www.w3.org/2000/01/rdf-schema#comment | "Dopamine supersensitivity occurs in schizophrenia and other psychoses, and after hippocampal lesions, antipsychotics, ethanol, amphetamine, phencyclidine, gene knockouts of Dbh (dopamine beta-hydroxylase), Drd4 receptors, Gprk6 (G protein-coupled receptor kinase 6), Comt (catechol-O-methyltransferase), or Th-/-, DbhTh/+ (tyrosine hydroxylase), and in rats born by Cesarean-section. The functional state of D2, or the high-affinity state for dopamine (D2High), was measured in these supersensitive animal brain striata. Increased levels and higher proportions (40-900%) for D2High were found in all these tissues. If many types of brain impairment cause dopamine behavioral supersensitivity and a common increase in D2High states, it suggests that there are many pathways to psychosis, any one of which can be disrupted."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0409766102"xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "George S.R."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Seeman P."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Robinson S."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Premont R.T."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Palmiter R.D."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Grandy D.K."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Sotnikova T.D."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Quirion R."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Weinshenker D."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Tallerico T."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Bhardwaj S.K."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Srivastava L.K."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Boksa P."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "El-Ghundi M."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Mannisto P.T."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "O'dowd B.F."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/author | "Perreault M.L."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/pages | "3513-3518"xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/title | "Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis."xsd:string |
http://purl.uniprot.org/citations/15716360 | http://purl.uniprot.org/core/volume | "102"xsd:string |