| http://purl.uniprot.org/citations/15716953 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15716953 | http://www.w3.org/2000/01/rdf-schema#comment | "Human vision starts with the activation of rod photoreceptors in dim light and short (S)-, medium (M)-, and long (L)-wavelength-sensitive cone photoreceptors in daylight. Recently a parallel, non-rod, non-cone photoreceptive pathway, arising from a population of retinal ganglion cells, was discovered in nocturnal rodents. These ganglion cells express the putative photopigment melanopsin and by signalling gross changes in light intensity serve the subconscious, 'non-image-forming' functions of circadian photoentrainment and pupil constriction. Here we show an anatomically distinct population of 'giant', melanopsin-expressing ganglion cells in the primate retina that, in addition to being intrinsically photosensitive, are strongly activated by rods and cones, and display a rare, S-Off, (L + M)-On type of colour-opponent receptive field. The intrinsic, rod and (L + M) cone-derived light responses combine in these giant cells to signal irradiance over the full dynamic range of human vision. In accordance with cone-based colour opponency, the giant cells project to the lateral geniculate nucleus, the thalamic relay to primary visual cortex. Thus, in the diurnal trichromatic primate, 'non-image-forming' and conventional 'image-forming' retinal pathways are merged, and the melanopsin-based signal might contribute to conscious visual perception."xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.org/dc/terms/identifier | "doi:10.1038/nature03387"xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/author | "Liao H.W."xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/author | "Yau K.W."xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/author | "Pokorny J."xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/author | "Smith V.C."xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/author | "Dacey D.M."xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/author | "Gamlin P.D."xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/author | "Peterson B.B."xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/author | "Robinson F.R."xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/pages | "749-754"xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/title | "Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN."xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://purl.uniprot.org/core/volume | "433"xsd:string |
| http://purl.uniprot.org/citations/15716953 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15716953 |
| http://purl.uniprot.org/citations/15716953 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15716953 |
| http://purl.uniprot.org/uniprot/#_A0A0S2RRN6-mappedCitation-15716953 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15716953 |
| http://purl.uniprot.org/uniprot/#_Q9UHM6-mappedCitation-15716953 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15716953 |
| http://purl.uniprot.org/uniprot/A0A0S2RRN6 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15716953 |
| http://purl.uniprot.org/uniprot/Q9UHM6 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15716953 |