http://purl.uniprot.org/citations/1572351 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1572351 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1572351 | http://www.w3.org/2000/01/rdf-schema#comment | "The primary structure of Pseudomonas 4-hydroxyphenylpyruvate dioxygenase was determined. Sequence degradation of the intact protein and of peptides from three different digests of the carboxymethylated protein established a 357-residue polypeptide chain with a free alpha-amino group. Hydroxylamine cleavage at a single Asn-Gly sequence was useful. Comparisons with known structures in data banks revealed no close relationship with other characterized proteins. The human enzyme has a related composition, suggesting that also the eukaryotic form belongs to this protein type, but with a blocked N-terminus like in many other eukaryotic intracellular proteins. Secondary structure predictions suggest an alpha/beta mixed structure, fairly typical of globular proteins, without long segments of hydrophobicity or charge, although a region in the middle of the C-terminal third of the subunit appears to have the most extreme properties. A ferric centre, correlating with enzyme activity and absorbance at 595 nm, has previously been assigned to tyrosinate coordination. The Tyr and His distributions, and the position of a single Cys residue, all suggest a few likely sites, outside the C-terminal segment, for this centre."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1432-1033.1992.tb16800.x"xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1432-1033.1992.tb16800.x"xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/author | "Joernvall H."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/author | "Joernvall H."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/author | "Barros-Soederling J."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/author | "Barros-Soederling J."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/author | "Lindstedt S."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/author | "Lindstedt S."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/author | "Odelhoeg B."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/author | "Odelhoeg B."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/author | "Persson B."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/author | "Persson B."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/author | "Rueetschi U."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/author | "Rueetschi U."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/name | "Eur. J. Biochem."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/name | "Eur. J. Biochem."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/pages | "459-466"xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/pages | "459-466"xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/title | "Characterization of 4-hydroxyphenylpyruvate dioxygenase. Primary structure of the Pseudomonas enzyme."xsd:string |
http://purl.uniprot.org/citations/1572351 | http://purl.uniprot.org/core/title | "Characterization of 4-hydroxyphenylpyruvate dioxygenase. Primary structure of the Pseudomonas enzyme."xsd:string |