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http://purl.uniprot.org/citations/15740584http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15740584http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15740584http://www.w3.org/2000/01/rdf-schema#comment"Cells of Dictyostelium discoideum become sexually mature under submerged and dark conditions, and fuse with opposite mating-type cells to form zygote giant cells, which gather surrounding cells and finally develop into dormant structures called macrocysts. In the present study, we found that the multinuclear fused cells formed during this process frequently underwent cytokinesis driven by random local movements. The split cells were capable of re-fusion, and repeated cytokinesis. These radical behaviors continued until the extensive cell aggregation started around the giant cells. Thus, gamete fusion and initiation of zygote development do not coincide in the mating of D. discoideum. Analyses by confocal microscopy and flow cytometry indicated that the cessation of the random movement followed pronuclear fusion, and that microtubule organizing centers (MTOC), abundant in the fused cells at the beginning, gradually decreased and only one of them remained within the developed macrocyst. Some of the genes known to control cell movement, such as rasGEFB and rasS, increased shortly before the cessation of repeated fusion-cytokinesis and initiation of phagocytosis. These results suggest that the sequential molecular events are necessary in D. discoideum after gamete fusion to establish a new individuality of zygotes."xsd:string
http://purl.uniprot.org/citations/15740584http://purl.org/dc/terms/identifier"doi:10.1111/j.1440-169x.2004.00776.x"xsd:string
http://purl.uniprot.org/citations/15740584http://purl.org/dc/terms/identifier"doi:10.1111/j.1440-169x.2004.00776.x"xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/author"Ishida K."xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/author"Ishida K."xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/author"Urushihara H."xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/author"Urushihara H."xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/author"Hata T."xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/author"Hata T."xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/name"Dev. Growth Differ."xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/name"Dev. Growth Differ."xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/pages"25-35"xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/pages"25-35"xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/title"Gamete fusion and cytokinesis preceding zygote establishment in the sexual process of Dictyostelium discoideum."xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/title"Gamete fusion and cytokinesis preceding zygote establishment in the sexual process of Dictyostelium discoideum."xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/volume"47"xsd:string
http://purl.uniprot.org/citations/15740584http://purl.uniprot.org/core/volume"47"xsd:string
http://purl.uniprot.org/citations/15740584http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15740584
http://purl.uniprot.org/citations/15740584http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15740584
http://purl.uniprot.org/citations/15740584http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15740584
http://purl.uniprot.org/citations/15740584http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15740584