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http://purl.uniprot.org/citations/15744341http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15744341http://www.w3.org/2000/01/rdf-schema#comment"Two microarray studies of mediastinal B cell lymphoma have shown that this disease has a distinct gene expression profile, and also that this is closest to the pattern seen in classical Hodgkin's disease. We reported previously an immunohistologic study in which the loss of intracellular B cell-associated signaling molecules in Reed-Sternberg cells was demonstrated, and in this study we have investigated the expression of the same components in more than 60 mediastinal B cell lymphomas. We report that these signaling molecules are frequently present, and in particular that Syk, BLNK and PLC-gamma2 (absent from Reed-Sternberg cells) are present in the majority of mediastinal B cell lymphomas. The overall pattern of B cell signaling molecules in this disease is therefore closer to that of diffuse large B cell lymphoma than to Hodgkin's disease, and is consistent with a common cell of origin as an explanation of the similar gene expression profiles."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.org/dc/terms/identifier"doi:10.1038/sj.leu.2403702"xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Siebert R."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Ventura R."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Gascoyne R.D."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Mason D.Y."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Gaulard P."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Moller P."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Martin-Subero J.I."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Hsi E.D."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Marafioti T."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Natkunam Y."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Hansmann M.L."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Pileri S.A."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Roberton H."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Copie-Bergman C."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Barth T.F."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/author"Pozzobon M."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/name"Leukemia"xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/pages"856-861"xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/title"Expression pattern of intracellular leukocyte-associated proteins in primary mediastinal B cell lymphoma."xsd:string
http://purl.uniprot.org/citations/15744341http://purl.uniprot.org/core/volume"19"xsd:string
http://purl.uniprot.org/citations/15744341http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15744341