| http://purl.uniprot.org/citations/15750187 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15750187 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15750187 | http://www.w3.org/2000/01/rdf-schema#comment | "Anteroposterior cell migration and patterning in C. elegans are governed by multiple, interacting signaling pathways and transcription factors. In this study, we have investigated the role of ceh-20, the C. elegans ortholog of the HOX co-factor Extradenticle (Exd/Pbx), and unc-62, the C. elegans ortholog of Homothorax (Hth/Meis/Prep), in two processes that are regulated by Hox gene lin-39: cell migration and vulva formation. As in lin-39 mutants, the anterior migrations of neuroblasts in the Q lineage are truncated in Hox co-factor mutants. Surprisingly, though, our findings suggested that the roles of ceh-20 and unc-62 are different from that of lin-39; specifically, ceh-20 and unc-62 but not lin-39 are required for the transmembrane protein MIG-13 to promote anterior migration. To our knowledge, ceh-20 and unc-62 are the only genes that have been implicated in the mig-13 pathway. We find that ceh-20 and unc-62 are also required for several steps in vulva development. Surprisingly, ceh-20 and unc-62 mutants have phenotypes that are starkly different from those of lin-39 mutants. Thus, in this process, too, ceh-20 and unc-62 are likely to have functions that are independent of lin-39."xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.01569"xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.01569"xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/author | "Yang L."xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/author | "Yang L."xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/author | "Kenyon C."xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/author | "Kenyon C."xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/author | "Sym M."xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/author | "Sym M."xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/name | "Development"xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/name | "Development"xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/pages | "1413-1428"xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/pages | "1413-1428"xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/title | "The roles of two C. elegans HOX co-factor orthologs in cell migration and vulva development."xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/title | "The roles of two C. elegans HOX co-factor orthologs in cell migration and vulva development."xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/volume | "132"xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://purl.uniprot.org/core/volume | "132"xsd:string |
| http://purl.uniprot.org/citations/15750187 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15750187 |
| http://purl.uniprot.org/citations/15750187 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15750187 |
| http://purl.uniprot.org/citations/15750187 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15750187 |
| http://purl.uniprot.org/citations/15750187 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15750187 |