| http://purl.uniprot.org/citations/15750595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15750595 | http://www.w3.org/2000/01/rdf-schema#comment | "The genetic programs directing CD4 or CD8 T cell differentiation in the thymus remain poorly understood. While analyzing gene expression during intrathymic T cell selection, we found that Zfp67, encoding the zinc finger transcription factor cKrox, was upregulated during the differentiation of CD4(+) but not CD8(+) T cells. Expression of a cKrox transgene impaired CD8 T cell development and caused major histocompatibility complex class I-restricted thymocytes to differentiate into CD4(+) T cells with helper properties rather than into cytotoxic CD8(+) T cells, as normally found. CD4 lineage differentiation mediated by cKrox required its N-terminal BTB (bric-a-brac, tramtrack, broad complex) domain. These findings identify cKrox as a chief CD4 differentiation factor during positive selection."xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni1183"xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/author | "Liu X."xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/author | "Sun G."xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/author | "Feigenbaum L."xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/author | "Bosselut R."xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/author | "Galera P."xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/author | "Kypriotou M."xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/author | "Mercado P."xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/author | "Jenkinson S.R."xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/name | "Nat Immunol"xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/pages | "373-381"xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/title | "The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection."xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://purl.uniprot.org/core/volume | "6"xsd:string |
| http://purl.uniprot.org/citations/15750595 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15750595 |
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