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http://purl.uniprot.org/citations/15752751http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15752751http://www.w3.org/2000/01/rdf-schema#comment"In this study, we determined the role of PDGF-D, a new member of the PDGF family, in a rat model of balloon injured artery made with a 2F catheter in Sprague-Dawley male rats. PDGF-D expression was studied in the injured and control segments of abdominal aorta. The function of PDGF-D was evaluated in rat vascular smooth muscle cells stably transfected with PDGF-D gene. We found that in normal abdominal aorta, PDGF-D was highly expressed in adventia, moderate in endothelia, and unidentified in media. Stable transfection of PDGF-D gene into vascular smooth muscle cells increased the cell migration by 2.2-fold, and the proliferation by 2.3-fold, respectively, and MMP-2 production and activity as well. These results support the fact that PDGF-D is involved in the formation of neointimal hyperplasia induced by balloon catheter injury and may serve as a target in preventing vascular restenosis after coronary angioplasty."xsd:string
http://purl.uniprot.org/citations/15752751http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2005.02.062"xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/author"Chen J."xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/author"Chen Y."xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/author"Chen C."xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/author"Han Y."xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/author"Song X."xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/author"Lin C."xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/author"Zhang Y."xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/author"Zhen Y."xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/author"Hui R."xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/author"Teng S."xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/name"Biochem Biophys Res Commun"xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/pages"976-983"xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/title"PDGF-D contributes to neointimal hyperplasia in rat model of vessel injury."xsd:string
http://purl.uniprot.org/citations/15752751http://purl.uniprot.org/core/volume"329"xsd:string
http://purl.uniprot.org/citations/15752751http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15752751
http://purl.uniprot.org/citations/15752751http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15752751
http://purl.uniprot.org/uniprot/Q9EQT1#attribution-717192838E0D35E2480CC5C0A84C4D7Ahttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/15752751
http://purl.uniprot.org/uniprot/Q9EQT1#attribution-7AAE5E126F72880EF98BAE596A243DA0http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/15752751
http://purl.uniprot.org/uniprot/#_A0A096MJ33-mappedCitation-15752751http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15752751
http://purl.uniprot.org/uniprot/#_A6JN21-mappedCitation-15752751http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15752751
http://purl.uniprot.org/uniprot/#_A6JN22-mappedCitation-15752751http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15752751