| http://purl.uniprot.org/citations/15753162 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15753162 | http://www.w3.org/2000/01/rdf-schema#comment | "The Alpha-Tocopherol Beta-Carotene Cancer Prevention Study has provided the first evidence implicating vitamin E in hormone synthesis. The effect of vitamin E on stereoidogenesis in testes and adrenal glands was assessed in growing rats using Affymetrix gene-chip technology. Dietary supplementation of rats with vitamin E (60 mg/kg feed) for a period of 429 days caused a significant repression of genes encoding for proteins centrally involved in the uptake (low-density lipoprotein receptor) and de novo synthesis (for example, 7-dehydrocholesterol reductase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, isopentenyl-diphosphate delta-isomerase, and farnesyl pyrophosphate synthetase) of cholesterol, the precursor of all steroid hormones. The present investigation indicates that dietary vitamin E may induce changes in stereoidogenesis by affecting cholesterol homeostasis."xsd:string |
| http://purl.uniprot.org/citations/15753162 | http://purl.org/dc/terms/identifier | "doi:10.1196/annals.1331.036"xsd:string |
| http://purl.uniprot.org/citations/15753162 | http://purl.uniprot.org/core/author | "Barella L."xsd:string |
| http://purl.uniprot.org/citations/15753162 | http://purl.uniprot.org/core/author | "Stocklin E."xsd:string |
| http://purl.uniprot.org/citations/15753162 | http://purl.uniprot.org/core/author | "Rimbach G."xsd:string |
| http://purl.uniprot.org/citations/15753162 | http://purl.uniprot.org/core/author | "Rota C."xsd:string |
| http://purl.uniprot.org/citations/15753162 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15753162 | http://purl.uniprot.org/core/name | "Ann N Y Acad Sci"xsd:string |
| http://purl.uniprot.org/citations/15753162 | http://purl.uniprot.org/core/pages | "334-336"xsd:string |
| http://purl.uniprot.org/citations/15753162 | http://purl.uniprot.org/core/title | "Alpha-tocopherol affects androgen metabolism in male rat."xsd:string |
| http://purl.uniprot.org/citations/15753162 | http://purl.uniprot.org/core/volume | "1031"xsd:string |
| http://purl.uniprot.org/citations/15753162 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15753162 |
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