http://purl.uniprot.org/citations/15761153 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15761153 | http://www.w3.org/2000/01/rdf-schema#comment | "Signaling pathways transmit information through protein interaction networks that are dynamically regulated by complex extracellular cues. We developed LUMIER (for luminescence-based mammalian interactome mapping), an automated high-throughput technology, to map protein-protein interaction networks systematically in mammalian cells and applied it to the transforming growth factor-beta (TGFbeta) pathway. Analysis using self-organizing maps and k-means clustering identified links of the TGFbeta pathway to the p21-activated kinase (PAK) network, to the polarity complex, and to Occludin, a structural component of tight junctions. We show that Occludin regulates TGFbeta type I receptor localization for efficient TGFbeta-dependent dissolution of tight junctions during epithelial-to-mesenchymal transitions."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1105776"xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Hayashizaki Y."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Liu Y."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Liu Z."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Robinson M."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Suzuki H."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Brown K.R."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Wrana J.L."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Bose R."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Dembowy J."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Taylor I.W."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Jurisica I."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Barrios-Rodiles M."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Ozdamar B."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Donovan R.S."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Luga V."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Przulj N."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/author | "Shinjo F."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/pages | "1621-1625"xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/title | "High-throughput mapping of a dynamic signaling network in mammalian cells."xsd:string |
http://purl.uniprot.org/citations/15761153 | http://purl.uniprot.org/core/volume | "307"xsd:string |