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http://purl.uniprot.org/citations/15765918 | http://www.w3.org/2000/01/rdf-schema#comment | "Constitutive expression of human achaete-scute homolog-1 (hASH-1) in combination with simian virus large Tantigen under the Clara cell 10-kDa secretory protein (CC10) promoter results in adenocarcinomas with focal neuroendocrine (NE) differentiation. Mice carrying conditional alleles for both Rb-1 and p53 in lung epithelial cells develop aggressive lung tumors with similarities to human small cell lung cancers, including high level expression of ASH-1, NE markers, and extra-pulmonary metastases. Tumors in both models originate from bronchiolar epithelium, reveal a range of premalignant changes, express thyroid transcription factor-1 (TTF-1), a marker of peripheral airway cell lineage, and display varying degrees of bidirectional epithelial/NE differentiation."xsd:string |
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http://purl.uniprot.org/citations/15765918 | http://purl.uniprot.org/core/author | "Berns A."xsd:string |
http://purl.uniprot.org/citations/15765918 | http://purl.uniprot.org/core/author | "DeMayo F.J."xsd:string |
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http://purl.uniprot.org/citations/15765918 | http://purl.uniprot.org/core/author | "Meuwissen R."xsd:string |
http://purl.uniprot.org/citations/15765918 | http://purl.uniprot.org/core/author | "Naizhen X."xsd:string |
http://purl.uniprot.org/citations/15765918 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15765918 | http://purl.uniprot.org/core/name | "Exp Lung Res"xsd:string |
http://purl.uniprot.org/citations/15765918 | http://purl.uniprot.org/core/pages | "37-55"xsd:string |
http://purl.uniprot.org/citations/15765918 | http://purl.uniprot.org/core/title | "Mouse lung neuroendocrine carcinomas: distinct morphologies, same transcription factors."xsd:string |
http://purl.uniprot.org/citations/15765918 | http://purl.uniprot.org/core/volume | "31"xsd:string |
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