| http://purl.uniprot.org/citations/15789425 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15789425 | http://www.w3.org/2000/01/rdf-schema#comment | "To generate temporally controlled targeted somatic mutations selectively and efficiently in skeletal muscles, we established a transgenic HSA-Cre-ER(T2) mouse line in which the expression of the tamoxifen-dependent Cre-ER(T2) recombinase is under the control of a large genomic DNA segment of the human skeletal muscle alpha-actin gene, contained in a P1-derived artificial chromosome. In this transgenic line Cre-ER(T2) is selectively expressed in skeletal muscles, and Cre-ER(T2)-mediated alteration of LoxP flanked (floxed) target genes is skeletal muscle-specific and strictly tamoxifen-dependent. HSA-Cre-ER(T2) mice should be of great value to analyze gene function in skeletal muscles, and to establish animal models of human skeletal muscle disorders."xsd:string |
| http://purl.uniprot.org/citations/15789425 | http://purl.org/dc/terms/identifier | "doi:10.1002/gene.20107"xsd:string |
| http://purl.uniprot.org/citations/15789425 | http://purl.uniprot.org/core/author | "Schuler M."xsd:string |
| http://purl.uniprot.org/citations/15789425 | http://purl.uniprot.org/core/author | "Ali F."xsd:string |
| http://purl.uniprot.org/citations/15789425 | http://purl.uniprot.org/core/author | "Metzger E."xsd:string |
| http://purl.uniprot.org/citations/15789425 | http://purl.uniprot.org/core/author | "Chambon P."xsd:string |
| http://purl.uniprot.org/citations/15789425 | http://purl.uniprot.org/core/author | "Metzger D."xsd:string |
| http://purl.uniprot.org/citations/15789425 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15789425 | http://purl.uniprot.org/core/name | "Genesis"xsd:string |
| http://purl.uniprot.org/citations/15789425 | http://purl.uniprot.org/core/pages | "165-170"xsd:string |
| http://purl.uniprot.org/citations/15789425 | http://purl.uniprot.org/core/title | "Temporally controlled targeted somatic mutagenesis in skeletal muscles of the mouse."xsd:string |
| http://purl.uniprot.org/citations/15789425 | http://purl.uniprot.org/core/volume | "41"xsd:string |
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